-mabs

Question 1

Alemtuzumab

Answer 1

CD52

Question 2

Bevacizumab

Answer 2

BEGF

Question 3

Cetuximab

Answer 3

EGFR

Question 4

Rituximab

Answer 4

CD20

Question 5

Trastuzumab

Answer 5

HER2/neu

Question 6

Topoisomerase inhib phase

Answer 6

S and G2

Question 7

Antimetabolite phase

Answer 7

S

Question 8

Cell cycle-indep drugs

Answer 8

Platinum

Alkylating

Question 9

MT inhibitors

Answer 9

M

Question 10

What is minoxidil used for?

Answer 10

alopecia (art vasodil)

Question 11

What is tamsulosin?

Answer 11

alpha 1 antag for BPH

Question 12

What is danazol?

Answer 12

partial agonist at androgen receptors (used for endometriosis and hereditary angioedema)

Question 13

Name me some aromatase inhibitors

Answer 13

Anastrozole, letrozole, exemestane

Question 14

Adalimumab

Answer 14

TNF-alpha

Question 15

Certolizumab

Answer 15

TNF-alpha

Question 16

Infliximab

Answer 16

TNF-alpha

Question 17

Eculizumab

Answer 17

Complement C5 (for Paroxysmal nocturnal hemoglobinuria)

Question 18

Natalizumab

Answer 18

alpha4-integrin (for MS and Crohn’s)

Question 19

Abciximab

Answer 19

Plt IIb/IIIa

Question 20

Denosumab

Answer 20

RANKL

Question 21

Palivizumab

Answer 21

RSV F protein

Question 22

Ranibizumab

Answer 22

VEGF

Question 23

Bevacizumab

Answer 23

VEGF

Question 24

Omalizumab

Answer 24

IgE (for asthma)

Question 25

Basiliximab

Answer 25

IL-2R

Question 26

Daclizumab

Answer 26

IL-2R

Question 27

Cyclosporine

Answer 27

Calcineurin inhib (cyclophilin) inhibits NFAT TF to activate

Question 28

Tacrolimus

Answer 28

Calcineurin inhib (FKBP) inhibit NFAT TF to activate

Question 29

Aldesleukin

Answer 29

IL-2 analog (for RCC and melanoma)

Question 30

Romiplostim, eltrombopag

Answer 30

Thrombopoitein agonist

Question 31

Oprelvekin

Answer 31

IL-11 for thrombocytopenia

Question 32

Sirolilmus (rapamycin)

Answer 32

mTOF inhibitor (from IL-2R)

Question 33

Mycopenholate

Answer 33

inhib IMP dehydrogenase

Question 34

Azathioprine

Answer 34

becomes 6-MP to inhibit PRPP amidotransferase to decrease purine synth

Question 35

Corticosteroids

Answer 35

inhibit NF-KB and inflammatory cytokine genes (inhib phospholipase 2 to reduce AA metab)