Cell Surface Proteins Flashcards
1
Q
Helper T cells (Th) markers
A
CD4, CD40L
2
Q
Cytotoxic T cells
A
CD8
3
Q
Tregs
A
CD4, CD25
4
Q
T cells in general
A
TCR (binds Ag-MHC)
CD3 (assoc with TCR for signal transduction)
CD28 (binds B7 on APC)
CXCR4/CCR5 (HIV)
5
Q
B cells
A
CD19, 20, 21 (EBV)
CD40
MHC II, B7
6
Q
Macs
A
CD14/TLR4 (receptor for PAMPs like LPS) CD40 CCR5 MHC II, B7 (CD80/86) Fc and C3b (opsonizing like Ab)
7
Q
NK cells
A
CD56 (unique marker for NK)
CD16
8
Q
Hematopoietic stem cells
A
CD34
9
Q
What are RBCs lacking in Nocturnal Paroxysmal Hemaglobinuria?
A
CD55/59
10
Q
B-ALL markers
A
- TdT
- CD19
- CD10
11
Q
T-ALL markers
A
- TdT
- Cd2-5
- CD-7
- CD-8
- CD1a sometimes
12
Q
CLL/SLL marker (Mature B-cell leukemia)
A
- CD19
- CD5 (coexpress T-cell marker)
13
Q
Reed-Sternberg cells are derived from which WBC?
A
B- cells usually
