Rate Limting Enzymes Flashcards

1
Q

RLS Glycolysis

A

Phosphofructokinase -1 (PFK-1)

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2
Q

RLS Gluconeogenesis

A

Fructose 1,6, bisphosphatase

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3
Q

RLS TCA Cycle

A

Isocitrate dehydrogenase

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4
Q

RLS Glycogenesis

A

Glycogen synthase

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5
Q

RLS Glycogenolysis

A

Glycogen phosphorylase

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6
Q

RLS HMP Shunt

A

Glucose 6 phosphate dehydrogenase (G6PD)

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7
Q

RLS De novo pyrimidine synthesis

A

Carbomoyl phosphate synthetase 2

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8
Q

RLS De novo purine synthesis

A

Glutamine phophoribosylpyrophosphate (PRPP) amidotransferase

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9
Q

RLS Urea Cycle

A

Carbomyl phosphate synthetase 1

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10
Q

RLS Fatty acid synthesis

A

Acetyl-CoA carboxylase (ACC)

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11
Q

RLS Fatty acid oxidation

A

Carnitine acyltransferase 1

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12
Q

RLS Ketogenesis

A

HMG CoA synthase

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13
Q

RLS Cholesterol synthesis

A

HMG CoA reductase

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14
Q

RLS Bile acid synthesis

A

7-alpha-hydroxylase

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15
Q

RLS Heme synthesis

A

Aminolevulinate synthase

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16
Q

Irreversible enzymes of gluconeogenesis

A

Pyruvate carboxylase + biotin
PEP carboxylase
Fructose 1-6bisphosphatase
Glucose 6 phosphatase