June 3rd

Question 1

Birbeck granule

Answer 1

EM of dendritic cell with Langerhans cell histiocytosis

Question 2

What causes the LES to relax?

Answer 2

NO

Question 3

Medical tx for alcohol withdrawl

Answer 3

Benzos

Question 4

Enzyme responsible for tRNA charging

Answer 4

Aminoacyl tRNA syntheses

Question 5

Side effect of Clozapine

Answer 5

Agranulocytosis

Question 6

Side effect of Olanzapine

Answer 6

Weight gain and diabetes

Question 7

Recurrent Neisseria infections caused by what complement deficiency

Answer 7

MAC Complex any of C5-C9

Question 8

Acute gout exacerbation Tx

Answer 8

NSAIDS–> Indomethacin
Colchicine
Corticosteroids

Question 9

Infxn with an IL-12 deficiency

Answer 9

Mycobacterial

Question 10

Triad of Sjogrens Syndrome

Answer 10

Xeropthalmia
Xerostomia
Arthritis

Question 11

Ebstein Anomaly

Answer 11

Tricuspid leaflets displaced inferiorly
RV hypoplasia
Tricuspid stenosis/regurg
+/- patent foramen ovale

Question 12

SE of TCA’s

Answer 12

Cardiotoxic = prolong QT, cause postural hypotension, arrhythmias
CNS toxicity = confusion and hallucinations
AntiCholinergic = tachy, urinary retention and dry mouth

Question 13

Antidepressant without sexual dysfunction

Answer 13

Buproprion

Question 14

Antidepressant causing priapsm

Answer 14

Trazdone “TrazoBONE”

Question 15

What antidepressant lowers the seizure threshold?

Answer 15

Buproprion

Question 16

Elderly depressed lady who needs to eat more

Answer 16

Mirtazapine

Question 17

Serotonin Syndrome Triad and Tx

Answer 17

Altered Mental Status
Autonomic Hyperactivity
Neuromuscular abnormalities
Tx with Benzos and cyproheptadine

Question 18

Major side effect for MAOI’s

Answer 18

Hypertensive crisis due to ingestion of tyramine found in many aged foods like cheese and wine

Question 19

Tricyclic OD Antidote

Answer 19

Sodium bicarb to prevent arrhythmia and trap weak acid in urine

Question 20

Polymyositis vs Polymyalgia Rheumatica

Answer 20

PM= muscle weakness, increased CK, aldolase +ANA and +Antijo1
PMR = joint pain but no muscle weakness or pain, normal CK/aldolase

Question 21

Tx of guys who needs an MRI but is too claustrophobic for one

Answer 21

Benzos

Question 22

Which personality disorder has a high rate of suicide?

Answer 22

Borderline personality disorder

Question 23

Which personality disorder uses splitting as a defense mechanism?

Answer 23

Borderline personality disorder

Question 24

CREST Scleroderma Sx

Answer 24

Calcinosis 
Raynauds 
Esophageal dysmotility 
Sclerodactyl 
Telangiectasias

Question 25

Pencillin MOA and Bacteriocidal/Bacteriostatic?

Answer 25

Binds to PBP and blocks transpeptidase cross linking
Activates autolytic enzymes that break down cell wall
Bacteriocidal

Question 26

Adult smooth part of right atrium arises from

Answer 26

Right horn sinus venosus

Question 27

Adult smooth ventricles

Answer 27

Bulbus cordis

Question 28

Adult smooth left atrium

Answer 28

Pulmonary veins

Question 29

Adult coronary sinus

Answer 29

Left horn sinus venosus

Question 30

Adult SVC

Answer 30

Embryonic right common and anterior cardiac veins

Question 31

Three stimulaters of renin release

Answer 31

B-adrenergic stimulation
Low Na in distal convoluted tubule (sensed by macula densa)
Low BP in afferent arteriole (sensed by JG cells)

Question 32

What happens when there is low Na in the distal convoluted tubule and who senses this?

Answer 32

Sensed by macula densa –> stimulates renin release by the JG cells

Question 33

What are the functions of renin?

Answer 33

Vasoconstriction and stimulation of the adrenal glands to produce more aldosterone

Question 34

What do the ureters pass under in males/females?

Answer 34

Pass under the uterine artery in females and the ductus deferens in males