June 3rd Flashcards

1
Q

Birbeck granule

A

EM of dendritic cell with Langerhans cell histiocytosis

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2
Q

What causes the LES to relax?

A

NO

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3
Q

Medical tx for alcohol withdrawl

A

Benzos

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4
Q

Enzyme responsible for tRNA charging

A

Aminoacyl tRNA syntheses

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5
Q

Side effect of Clozapine

A

Agranulocytosis

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6
Q

Side effect of Olanzapine

A

Weight gain and diabetes

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7
Q

Recurrent Neisseria infections caused by what complement deficiency

A

MAC Complex any of C5-C9

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8
Q

Acute gout exacerbation Tx

A

NSAIDS–> Indomethacin
Colchicine
Corticosteroids

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9
Q

Infxn with an IL-12 deficiency

A

Mycobacterial

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10
Q

Triad of Sjogrens Syndrome

A

Xeropthalmia
Xerostomia
Arthritis

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11
Q

Ebstein Anomaly

A

Tricuspid leaflets displaced inferiorly
RV hypoplasia
Tricuspid stenosis/regurg
+/- patent foramen ovale

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12
Q

SE of TCA’s

A

Cardiotoxic = prolong QT, cause postural hypotension, arrhythmias
CNS toxicity = confusion and hallucinations
AntiCholinergic = tachy, urinary retention and dry mouth

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13
Q

Antidepressant without sexual dysfunction

A

Buproprion

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14
Q

Antidepressant causing priapsm

A

Trazdone “TrazoBONE”

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15
Q

What antidepressant lowers the seizure threshold?

A

Buproprion

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16
Q

Elderly depressed lady who needs to eat more

A

Mirtazapine

17
Q

Serotonin Syndrome Triad and Tx

A

Altered Mental Status
Autonomic Hyperactivity
Neuromuscular abnormalities
Tx with Benzos and cyproheptadine

18
Q

Major side effect for MAOI’s

A

Hypertensive crisis due to ingestion of tyramine found in many aged foods like cheese and wine

19
Q

Tricyclic OD Antidote

A

Sodium bicarb to prevent arrhythmia and trap weak acid in urine

20
Q

Polymyositis vs Polymyalgia Rheumatica

A
PM= muscle weakness, increased CK, aldolase +ANA and +Antijo1
PMR = joint pain but no muscle weakness or pain, normal CK/aldolase
21
Q

Tx of guys who needs an MRI but is too claustrophobic for one

22
Q

Which personality disorder has a high rate of suicide?

A

Borderline personality disorder

23
Q

Which personality disorder uses splitting as a defense mechanism?

A

Borderline personality disorder

24
Q

CREST Scleroderma Sx

A
Calcinosis 
Raynauds 
Esophageal dysmotility 
Sclerodactyl 
Telangiectasias
25
Pencillin MOA and Bacteriocidal/Bacteriostatic?
Binds to PBP and blocks transpeptidase cross linking Activates autolytic enzymes that break down cell wall Bacteriocidal
26
Adult smooth part of right atrium arises from
Right horn sinus venosus
27
Adult smooth ventricles
Bulbus cordis
28
Adult smooth left atrium
Pulmonary veins
29
Adult coronary sinus
Left horn sinus venosus
30
Adult SVC
Embryonic right common and anterior cardiac veins
31
Three stimulaters of renin release
B-adrenergic stimulation Low Na in distal convoluted tubule (sensed by macula densa) Low BP in afferent arteriole (sensed by JG cells)
32
What happens when there is low Na in the distal convoluted tubule and who senses this?
Sensed by macula densa --> stimulates renin release by the JG cells
33
What are the functions of renin?
Vasoconstriction and stimulation of the adrenal glands to produce more aldosterone
34
What do the ureters pass under in males/females?
Pass under the uterine artery in females and the ductus deferens in males