Fungi/Protozoa/Helminths Flashcards
Associated with plant thorns and cutaneous injury
Sporthrix schenckii “rose gardeners disease”
Found in bird and bat droppings
Histoplasmosis
Mold form contains barrel-shaped arthroconidia
Coccidiodomycosis
Associated with dust storms
Coccidiodomycosis
Broad based budding
Blastomycosis
Multiple budding yeast form
Paracoccidioidomycosis
Latin America
Paracoccidioidomycosis
Captains wheel
Paracoccidioidomycosis
“Parasail to Latin American with the captain’s wheel”
Smaller than RBC
Histo
Same size as RBC
Blasto
Larger than RBC
Coccid
Infections associated with birds (5)
Cryptococcus Histoplasma Chlamydophila psittaci West Nile H5N1
Treatment for Sporothrix schenckii
Itraconazole
Potassium iodide
Puppy bite
Yersinia
Animal urine
Leptospira
Hantavirus
Dimorphic fungi form at cold (20degrees) and warm (37degrees)
Cold = mold Heat = yeast
What doesn’t form a yeast in tissue?
Coccidiodomycosis forms spherule
Spherule in tissue
Coccidiodomycosis
Infects macrophages
Histoplasmosis
“hides in macrophages”
Granulomatous nodules on skin
Blasto
Mycerial in soil
Coccidiodomycosis
Tinea dermatophyte classes
Microsporum
Trichophyton
Epidermophyton
Branching septae hyphae visible on KOH prep with blue fungal stain
Tinea (dermatophytes)
Microsporum
Trichophyton
Epidermophyton
Cause of onchomycosis (thickened discolored nails)
Tinea unguium
Cause of tinea versicolor
Malassezia furfur
Yeast like fungus
Hypo pigmented skin or pink patches
Scaling plaque but not puritic
In the summer
Tinea versicolor caused by malassezia furfur
Spaghetti and meatballs appearance
Tinea versicolor caused by malessezia furfur
Narrow septate hyphe branch at 45 degrees
Aspergillus fumigatus
AIDS patient with meningitis
Cryptococcus
Heavily encapsulated yeast
Cryptococcus
Tx of Cryptococcus
Amphoteracin B + Flucotosine (Fluconazole)
Stains with India ink
Cryptococcus
Latex agglutination detects polysaccharide capsule
Cryptococcus
Soap bubble lesions in the brain
Cryptococcus
Narrow based budding with wide capsular halos
Cryptococcus
Broad irregular nonspetae hype branch at 90 degrees wide
Mucor
Rhizopus
Fungal infection in DKA
Mucor/Rhizopus
Proliferate in blood vessels and penetrate cribriform plate
Mucor/Rhizopus
Frontal lobe abscess
Cavernous sinus thrombosis
Black necrotic eschar on face
Cranial nerve involvement
Mucor/Rhizopus
Diffuse interstitial pneumonia in AIDS patients
PCP
Diffuse bilateral ground glass opacities on CXR
PCP
Disc shaped yeast on methenamine silver stain
PCP
Tx/Prophylaxis for PCP
TMP-SMX
Rose gardeners disease
Sporothrix Schneckii
Local pustule or ulcers draining along lymphatics
Sporothrix Schneckii
Double nuclei “owl’s eyes”
Giardia lambia
Transmission through cysts in water
Giardia
Enatmoeba
Bloody diarrhea with liver abscess
RUQ pain
Flask shaped ulcers
Entamoeba histolytica
Trophozites interfere with fat absorption
Giardia
Severe diarrhea in AIDS
Water diarrhea in IC
Cryptosporidum
Oocysts on acid fast stain
Cryptosporidum
Prevented by filtering facilities
Cryptosporidium
Narrow septate hyphe branch at 45 degrees
Aspergillus fumigatus
AIDS patient with meningitis
Cryptococcus
Heavily encapsulated yeast
Cryptococcus
Rapidly fatal meningoencephalitis from swimming in freshwater lakes
Naegleria fowleri