June 17th Flashcards

1
Q

Alk Phos Tumor Marker

A

Paget disease of bone

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2
Q

Alpha fetoprotein tumor marker

A

Heaptocellular carcioma

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3
Q

CA19-9 tumor marker

A

Pancreatic adenocarcinoma

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4
Q

CEA tumor marker

A

Colorectal and pancreatic cancer

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5
Q

S-100 tumor marker

A

Melanoma
Schwanomma
Neural crest cells

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6
Q

TRAP tumor marker

A

Hairy Cell leukemia

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7
Q

EBV associated malignancies

A

Burkitt
Hodgkin
Nasopharyngeal carcinoma

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8
Q

Hep B/Hep C associated malignancies

A

Hepatocellular carcionma

Papillary thyroid carcinoma (Hep C)

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9
Q

Schistoma malignacies

A

Squamous cell bladder cancer

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10
Q

Asbestos exposure malignancy

A

Bronchogenic cariconma > mesothelioma

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11
Q

Tobacco smoke malignancy

A

Transitional cell bladder cancer

T for tobacco

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12
Q

Ionizing radiation malignancy

A

Papillary thyroid carcinoma

CML & AML

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13
Q

Small cell lung cancer paraneoplastic syndromes

A

ACTH
ADH
Lambert Eaton Myasthenic Syndrome
PTHrp

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14
Q

EPO producing tumors

A
"Potentially Really High Hematocrit" 
Phe
Renal CC 
Hemangioblastoma 
Hepatocellular CC
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15
Q

Metheglobin antidote

A

Methylene blue

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16
Q

Iron antidote

A

EDTA
Dimercaperol
Succinme

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17
Q

Cyanide antidote

A

Nitrates
Thiosulfate
Hydroxycobalamin

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18
Q

B-blocker antidote

A

Glucagon
Atropine
Calcium

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19
Q

tPA, streptokinase, urokinase antidote

A

Aminocaproic acid

20
Q

Heparin antidote

A

Protamine sulfate

21
Q

Rituximab

22
Q

Abciximab

A

Platelet glycoproteins IIb/IIIa

23
Q

Omalizumab

A

IgE target

24
Q

Trastuzumab

25
Adalimumab | Infliximab
Soluble TNF-a
26
Etancerpt
Decoy TNFa receptor
27
IFN-a Txs
Chronic Hep B and C Kaposi sarcoma Malignant melanoma
28
IFN-b Txs
MS
29
IFN-g Tx
Chronic granulomatous disease
30
Goodpasture Hypersensitivity
Type 2
31
Arthus rxn Hypersensitivity
Type 3
32
Serum sickness Hypersensitivity
Type 3
33
Autoimmune hemolytic anemia
Type 2
34
Liver transplant rejection chronic
Type 4
35
Humoral and cellular vaccine response
Live attenuated vaccine
36
Humoral vaccine response
Inactivated/killed vaccine
37
Receiving preformed Ab
Passive immunity
38
Anti-toxin passive or active?
Passive!!
39
What two vaccines are both passive and active?
Hep B and rabies
40
Attenuated live vaccines
``` "Attention! Please Vaccinate Young Infants with MMR Regularly" Poliovaccine (oral) Varicella Yellow fever Intranasal influenza MMR Rotovirus ```
41
P450 Inhibitors
``` "CRACK AMIGOS" Ciprofloxacin Ritonavir Amiodarone Cimitidine Ketoconazole Acute alcohol Macrolide INH Grapefruit juice Omeprazole Sulfonamides ```
42
P450 Inducers
``` "Guinness Coronas & PBRS induce Chronic Alcoholism" Griseofulvin Carbamazepine Phenytoin Barbiturates Rifampin St.Johns Wort Chronic Alcoholism ```
43
Drug Induced Lupus
``` "SHIPP" Sulfonamindes Hydralazine INH Procainamide Phenytoin ```
44
Nephrotoxicity + Ototoxicity
Aminoglycosides Vancomycin Loop diuretics cisplatin
45
Drugs causing gynecomastia
``` "Some Drugs Cause Awesome Knockers" Spironolactone Digitalis Cimitidine Alcohol Ketoconazole ```
46
Drugs Acting on Microtubulues
``` "Microtubules Get Constructed Very Poorly" Mebendazole Griseofulvin Colchicine Vincristine/Vinblastine Paclitaxel ```