June 17th Flashcards

1
Q

Alk Phos Tumor Marker

A

Paget disease of bone

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2
Q

Alpha fetoprotein tumor marker

A

Heaptocellular carcioma

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3
Q

CA19-9 tumor marker

A

Pancreatic adenocarcinoma

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4
Q

CEA tumor marker

A

Colorectal and pancreatic cancer

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5
Q

S-100 tumor marker

A

Melanoma
Schwanomma
Neural crest cells

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6
Q

TRAP tumor marker

A

Hairy Cell leukemia

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7
Q

EBV associated malignancies

A

Burkitt
Hodgkin
Nasopharyngeal carcinoma

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8
Q

Hep B/Hep C associated malignancies

A

Hepatocellular carcionma

Papillary thyroid carcinoma (Hep C)

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9
Q

Schistoma malignacies

A

Squamous cell bladder cancer

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10
Q

Asbestos exposure malignancy

A

Bronchogenic cariconma > mesothelioma

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11
Q

Tobacco smoke malignancy

A

Transitional cell bladder cancer

T for tobacco

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12
Q

Ionizing radiation malignancy

A

Papillary thyroid carcinoma

CML & AML

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13
Q

Small cell lung cancer paraneoplastic syndromes

A

ACTH
ADH
Lambert Eaton Myasthenic Syndrome
PTHrp

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14
Q

EPO producing tumors

A
"Potentially Really High Hematocrit" 
Phe
Renal CC 
Hemangioblastoma 
Hepatocellular CC
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15
Q

Metheglobin antidote

A

Methylene blue

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16
Q

Iron antidote

A

EDTA
Dimercaperol
Succinme

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17
Q

Cyanide antidote

A

Nitrates
Thiosulfate
Hydroxycobalamin

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18
Q

B-blocker antidote

A

Glucagon
Atropine
Calcium

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19
Q

tPA, streptokinase, urokinase antidote

A

Aminocaproic acid

20
Q

Heparin antidote

A

Protamine sulfate

21
Q

Rituximab

A

CD20

NHL

22
Q

Abciximab

A

Platelet glycoproteins IIb/IIIa

23
Q

Omalizumab

A

IgE target

24
Q

Trastuzumab

A

HER2/neu

25
Q

Adalimumab

Infliximab

A

Soluble TNF-a

26
Q

Etancerpt

A

Decoy TNFa receptor

27
Q

IFN-a Txs

A

Chronic Hep B and C
Kaposi sarcoma
Malignant melanoma

28
Q

IFN-b Txs

A

MS

29
Q

IFN-g Tx

A

Chronic granulomatous disease

30
Q

Goodpasture Hypersensitivity

A

Type 2

31
Q

Arthus rxn Hypersensitivity

A

Type 3

32
Q

Serum sickness Hypersensitivity

A

Type 3

33
Q

Autoimmune hemolytic anemia

A

Type 2

34
Q

Liver transplant rejection chronic

A

Type 4

35
Q

Humoral and cellular vaccine response

A

Live attenuated vaccine

36
Q

Humoral vaccine response

A

Inactivated/killed vaccine

37
Q

Receiving preformed Ab

A

Passive immunity

38
Q

Anti-toxin passive or active?

A

Passive!!

39
Q

What two vaccines are both passive and active?

A

Hep B and rabies

40
Q

Attenuated live vaccines

A
"Attention! Please Vaccinate Young Infants with MMR Regularly" 
Poliovaccine (oral) 
Varicella 
Yellow fever 
Intranasal influenza 
MMR 
Rotovirus
41
Q

P450 Inhibitors

A
"CRACK AMIGOS" 
Ciprofloxacin 
Ritonavir 
Amiodarone 
Cimitidine 
Ketoconazole 
Acute alcohol 
Macrolide 
INH 
Grapefruit juice 
Omeprazole 
Sulfonamides
42
Q

P450 Inducers

A
"Guinness Coronas & PBRS induce Chronic Alcoholism"
Griseofulvin 
Carbamazepine 
Phenytoin 
Barbiturates 
Rifampin 
St.Johns Wort 
Chronic Alcoholism
43
Q

Drug Induced Lupus

A
"SHIPP"
Sulfonamindes 
Hydralazine 
INH 
Procainamide 
Phenytoin
44
Q

Nephrotoxicity + Ototoxicity

A

Aminoglycosides
Vancomycin
Loop diuretics
cisplatin

45
Q

Drugs causing gynecomastia

A
"Some Drugs Cause Awesome Knockers"
Spironolactone 
Digitalis 
Cimitidine 
Alcohol 
Ketoconazole
46
Q

Drugs Acting on Microtubulues

A
"Microtubules Get Constructed Very Poorly" 
Mebendazole 
Griseofulvin 
Colchicine 
Vincristine/Vinblastine 
Paclitaxel