Pulmonary System Meds Flashcards
What do intranasal glucocorticoids do?
Decrease inflammation in the nose, treat allergic rhinitis
What drug class are fluticasone (Flonase) and triamcinolone (Nasacort)?
Intranasal glucocorticoids
diphenhydramine brand name
Benadryl
What effects do 1st gen antihistamines cause?
Anticholinergic, dry, can’t see/pee/spit/shit
What do you need to avoid when taking 1st gen antihistamine?
Alcohol and CNS depressants
One SE of 1st gen antihistamine is?
Drowsiness, so need to avoid driving
Difference between 2nd gen and 1st gen antihistamines?
2nd gen is less dry, and can be taken daily
Drug class of fexofenadine (Allegra) and loratadine (Claritin)
2nd gen antihistamine
Difference between what 1st and 2nd gen antihistamines treat?
1st gen: antitussive(镇咳)
2nd gen: urticaria (rash)
What to avoid when taking 2nd gen antihistamine?
Grapefruit juice
Drug class of oxymetazoline (Afrin) and pseudoephedrine (Sudafed)
Decongestant
What do decongestants do?
Vasoconstriction in nose
What class of drug do you need to avoid
MAOIs
How many days can you use nasal spray for?
Less than 5 days
What drug class is guaifenesin (Mucinex, Robitussin)
Expectorant
What do expectorants do?
Thin secretions
Pt education of expectorant
- Take with food b/c GI upset
- Increase fluid b/c water is the best natural expectorant
What drug class is dextromethorphan (Delsym)?
Antitussives
How do antitussives work?
Block cough reflex to stop coughs
What can antitussives combine with to make it the most effective?
Combine with codeine, makes narcotic
What class of drug to avoid when taking antitussives?
Antidepressants (MAOI, SSRI)
Can you use antitussives for chronic coughs?
No
When is the best time to take antitussives?
Before bed, b/c can make you drowsy
Drug class of oseltamivir phosphate (Tamiflu)
Anti-influenza
Drug class of zanamivir (Relenza)
Anti-influenza
What do anti-influenza drugs do?
Reduce the duration of flu, reduce symptoms, not cure
Best way to take anti-influenza drugs?
Take with food
What to watch for and report when taking anti-influenza drugs?
Report behavior changes b/c can cause seizure
Drug class of ribavirin (Virazole)
Antiviral
How to use ribavirin (Virazole)?
Continuous aerosol tx for 3-5 days
What is antiviral drugs used for?
Resp syncytial virus (RSV) in small infants and immunocompromised pt
Who do you need to educate for antiviral drugs?
Pt, workers and visitors, b/c serious side effects can occur with exposure
What drug class is epinephrine?
Bronchodilators
What do bronchodilators do?
Open up airways, bronchodilation
Drug class of fomoterol (Foradil)
Bronchodilators
Drug class of salmeterol (Serevent)
Bronchodilators
Beta-adrenergic agonist bronchodilators side effects
Fight or flight
Beta 2 adrenergic agonist uses
Used to open up large airways
Drug class of albuterol (Proventil, Ventolin)
Bronchodilators
What side effect does albuterol have?
Tremor
Drug class of metaproterenol (Alupent)
Bronchodilators
Anticholinergics uses in bronchodilator drug uses
Open up smaller airways, decrease bronchospasm
Drug class of ipratropium bromide (Atrovent)
Anticholinergic bronchodilators
What is the drug with Atrovent combined with albuterol?
Duoneb
Drug class of tiotropium (Spiriva)
Anticholinergic bronchodilatos
Pt education of anticholinergic bronchodilators after taking med
Rinse mouth with water to prevent oral thrush
Drug class of methylxanthines (Xanthines)
Bronchodilators
Oral forms of Xanthines
- aminophylline
- theophylline
amiphylline and theophylline uses
Maintenance for chronic stable asthma
What is aminophylline and theophylline’s narrow therapeutic range?
10-20 mcg/ml
Corticosteroids function
Decrease inflammation
Glucocorticoids function other than decrease inflammation
Suppress immune system
You can take glucocorticoids daily for what purpose
Prevent asthma attacks
Drug class of budesonide (Pulmicort)
Corticosteroids
Drug class of prednisone
Corticosteroids
Drug class of fluticasone (Flovent)
Corticosteroids
Oral glucocorticoids uses
Acute asthma
Methylprednisolone brand name
Solu-Medrol
Is glucocorticoids short term or long term?
Short term b/c suppress immune system
Proper way to discontinue glucocorticoids
Taper off
What drug class is Mast Cell Stabilizer under?
Corticosteroids
Whatbare mast cells?
Allergy cells
What do mast cell stabilizers do?
Prevent or decrease occurrence of asthma attacks
Do mast cell stabilizers help acute asthma attacks?
No
How long does it take for mast cell stabilizers to start working?
2-6 weeks
Drug class of cromolyn (Gastrocrom)
Mast cell stabilizer, corticosteroid
What does leukotriene receptor antagonists do?
Decrease inflammation, bronchodilation
How long does it take for leukotriene receptor antagonists to start working?
1 week
Most effective time to take leukotriene receptor antagonists is?
At night
Is leukotrien receptor antagonists routinely or PRN tx?
Rountinely
Drug class of zafirlukast (Accolate)
Leukotriene receptor antagonist
Drug class of montelukast (Singulair)
Leukotriene receptor antagonist
Adverse reaction of leukotriene receptor antagonists
Can cause suicidal thoughts and worsen depression
Mucolytics uses
Liquify thick lung secretions in cystic fibrosis
Drug class of acetylcysteine (Mucomyst)
Mycolytics
Order of med admin for asthma
Beta 2 adrenergic bronchodilator (albuterol), anticholinergic bronchodilator (tiotropium), glucocorticoids (bydesonide), mast cell stabilizer (cromolyn)
Only deliver amount ordered for O2 b/c?
Can damage eyes
What are respiratory stimulants used for?
Pt with apnea, stimulate resp center in the brain
Drug class of caffeine citrate (Cafcit)
Respiratory stimulant
What is nicotine transdermal patch called?
Nicoderm
What is nicotine gum called
Nicorette
What is nicotine inhalation called
Nicotrol
What is nicotine Nas spray called
Nicotrol
What is varenicline (Chantix) used for
Smoking cessation
Which antidepressant can be used for smoking cessation?
bupropion hydrochloride (Wellbutin, Zyban)