Antibiotics Flashcards
Bactericidal chinese
杀菌
Bacteriostatic chinese
抑菌
Are sulfonamides bactericidal or bacteriostatic?
Bacteriostatic
Drug class of trimethoprim/sulfamethoxazole (Bactrim, Septra)
Sulfonamides antibiotics
Drug class of sulfasalazine
Sulfonamides antibiotics
Sulfasalazine take with or without food?
With food
What can be used with antibiotics to prevent bacteria from attaching to urinary tract walls
Cranberry, reduce UTI
Sulfasalazine, like rifampin, can do what?
Turn body fluids orange
Sulfasalazine has what effect on contact lenses?
Permanently discolor the contact lenses, so wear glasses
All antibiotics have what side effects?
NVD, anorexia, abd pain
When giving sulfonamides to diabetic pt, need to monitor what?
Blood sugar level, because can cause hypoglycemia
How should you take sulfonamides?
With a full glass of water
Sulfonamides have which side effect that requires you to avoid sunlight?
Photosensitivity
Is it common for sulfonamides to cause body fluid discoloration?
Yes
Which gen of cephalosporin is cephalexin?
1st
Which gen of cephalosporin is cefaclor?
2nd
Which gen of cephalosporin is cefoperazone?
3rd
Which gen of cephalosporin is cefepime?
4th
Which gen or cephalosporin is ceftaroline?
5th
What are cephalosporin used for?
Resp infection, otitis media, bone/joint infections, can be given after sexual assault to prevent bacteria
What do sulfonamides interact with?
Anticoagulant, hydantoin, methotrexate
What do cephalosporin interact with?
Anticoagulants, aminoglycosides, loop diuretics
Amoxicillin, ampicillin, and piperacillin are examples of?
Penicillin
Amoxicillin + clavulanate
Augmentin
Piperacillin + tazobactam
Zosyn
What is penicillin used for?
UTI, meningitis, STI, pneumonia and other resp infections, intra-abd infections
SE of penicillin
Glossitis, stomatitis, gastritis, NVD, abd pain, phlebitis, pancytopenia, bone marrow depression
What does penicillin interact with?
Tetracycline, oral contraceptives, anticoagulant, beta blockers
Carbapenems uses
Complicated infections
Drug class of vancomycin
Carbapenem
If vancomycin is given too fast, what can happen?
Red man syndrome (rash in neck/skin/torso, low bp, chest pain, pale skin, petechiae, shortness of breath
What to do if you see red man syndrome caused by vancomycin?
Slow it down! Can give antihistamine
Drug class of oritavancin
Carbapenem
Drug class of telavancin
Carbapenem
Drug class of aztreonam
Carbapenem
Drug class of meropenem
Carbapenem
Side effects of carbapenem
NVD, nephrotoxicity, ototoxicity, low bp with IV
Vanco peak will happen when? And what is the normal level?
About 30 minutes after infusion, norm value 20-40 mg/ml
Vanco trough will happen when? And what is the normal value?
30 minutes before the next dose
Mild infection: 10 mcg/ml
Severe infection: 15-20 mcg/ml
Do you take penicillin with or without food?
Without
For cephalosporins, penicillin, and carbapenem, how should you store and do before taking the oral suspension?
Refrigerate, and shake well before admin
Drug class of vibramycin
Tetracycline
Drug class of doxycycline
Tetracycline
Tetracycline uses
E Coli, H Pylori, skin infections, resp infections
What can tetracyclines do to children less than 9 y.o.?
Cause permanent yellow gray brown discoloration of teeth
What do tetracyclines interact with?
Oral contraceptives, antacids, anticoagulants, digoxin
Drug class of gentamicin and neomycin
Aminoglycosides
What are aminoglycosides used for?
Abd surgery, hepatic coma
Adverse reactions of aminoglycosides
Nephrotoxicity, ototoxicity, and neurotoxicity
Can you use aminoglycosides if pt have myasthenia gravis?
No
Can younuse aminoglycosides if pt have hearing loss?
No
Can you use aminoglycosides if pt have Parkinson disease?
No
What do aminoglycosides interact with?
Cephalosporins
What are macrolides used for?
Gram pos and neg infections, acne and skin infections, upper resp infections, used for pt who are allergic to penicillins
Drug class of azitgromycin
Macrolides
Drug class of zithromax
Macrolides
Drug class of clarithromycin
Macrolides
What do macrolides interact with?
Antacids, digoxin, anticoagulants, theophylline, clindamycin, lincomycin
Drug class of cleocin
Lincosamides
Drug class of lincocin
Lincosamides
Drug class of clindamycin
Lincosamides
Lincosamides uses
Gram pos and neg infections
Can lincosamides be used for minor bacterial/viral infections?
No because this is high powered antibiotics
What is cubicin, zyvox, daptomycin, and linezolid used for?
Skin infections, MRSA
What can cubicin, zyvox, daptomycin, linezolid cause?
Depressions headache, dizziness, NVD, constipation
How should you take tetracyclines?
On an empty stomach
How should you take aminoglycosides?
With a full glass of water, take with food
How should you take macrolides?
With a full glass of water, take with food
How should you take lincosamides?
With a full glass of water, take with food
What kind of food need to be avoided when taking tetracyclines?
Food containing calcium
Drug class of ciprofloxacin
Fluoroquinolones
Drug class of delafloxacin
Fluoroquinolones
Drug class of levofloxacin
Fluoroquinolones
Fluoroquinolones uses
Lower resp infections, bone/joint infections, UTI, skin infections
Can you use fluoroquinolones in diabetic pt’s?
No
What to avoid while taking fluoroquinolones?
High intensity exercise b/c of increased risk of tendinitis and tendon rupture
What do fluoroquinolones interact with?
Anticoagulants, antacids, NSAIDs