Immunostimulants & Immunomodulators

Question 1

Interferons chinese

Answer 1

干扰素

Question 2

What are Alferon, Avonex, and PEG-intron

Answer 2

Interferons

Question 3

What are interferons used for?

Answer 3

Multiple sclerosis, inhibits tumors, stimulates T cells, prevent viruses

Question 4

Interferons can stimulate a system called hematopoietic system, what is it used for?

Answer 4

Used for cancer tx and chronic renal failure

Question 5

What is Colony-Stimulating Factors (CSF): neutrophils, used for?

Answer 5

Boost immune system.
Prevent infection associated with:
1. Neutropenia
2. Production of STEM cells for harvest
3. Neutropenia for symptomatic chronic failure

Question 6

Pt with what disease can you not give CSF-neutrophil to?

Answer 6

Sickle cell disease b/c can lead to sickle cell crisis

Question 7

What does CSF-neutrophil interact with?

Answer 7

Lithium

Question 8

Pegfilgrastim and filgrastim (Neupogen) drug class

Answer 8

CSF-neutrophil

Question 9

What do CSF-platelet dev do?

Answer 9

Low plt, low rbc.
Increase production of megakaryocytes (produce platelets in red bone marrow)

Question 10

What should you do prior to giving CSF-plt dev meds?

Answer 10

Liver study b/c some are toxic to the liver

Question 11

Drug class of eltrobopag, romiplostum, and avatrombopag

Answer 11

CSF-plt dev

Question 12

What are CSF-RBC dev meds used for?

Answer 12

Anemia.
HIV therapy, chemo, surgical blood replacement

Question 13

Drug class of dardepoetin alfa, methoxy polyethylene-opoetin B

Answer 13

CSF-RBC dev

Question 14

Iron deficiency pt needs to eat more of?

Answer 14

Eggs, poultry, fish, green leafy veggies, meat

Question 15

What is Leucovorin used for?

Answer 15

Rescue RBC

Question 16

What does leucovorin interact with?

Answer 16

Antiseizure meds

Question 17

Can you take iron with or without food?

Answer 17

Without

Question 18

What drugs can you not take with iron?

Answer 18

Tetracyclines, antacids, b/c may cause black stool, diarrhea, constipation