GU System Drugs

Question 1

Infertility/LH and LSF stimulant - clomud

Answer 1

Stimulate ovary to produce more follicles
Adv reac: GI symptoms, dizziness, hot flashes, breat engorgement
Route: PO, begin 5 days after cycle onset, repeat 30 days for conception
Don’t use in pregnancy, liver disease, primary ovarian failure, undiagnosed uterine bleeding
Pt edu: wear supportive bra, take med with food, expect hot flashes, can take OTC anti-inflammatory drugs PRN

Question 2

Benign Prostatic Hypertrophy drug therapy (BPH) - finasteride (Proscar)

Answer 2

Shrink prostate size
Route: PO, taken daily, not PRN
If taking for painful urination, it takes several months before will get better
Don’t use if have renal/hepatic disease, hypertension, angina, pregnancy
Women should not handle without gloves!
Don’t stop taking med even if symptoms get better b/c symptoms will come back!

Question 3

Erectile dysfunction - Viagra (sildenafil), Cialis (tadalafil)

Answer 3

Dilate circulatory vessels, more blood to pelvis
Route: PO
don’t use if men use nitrates for chest pain b/c will cause hypotension b/c opens up blood vessels
Pt edu: report headaches, dizziness, and erection > 4 hrs, call doctor if vision changed, check BP regularly, do not take this if taking nitrates for chest pain!

Question 4

Antispasmodics

Answer 4

Cholinergic blocking, relax bladder contractions
mirabegron (Myrbetriq): increase filling
Used to treat neurogenic bladder
Adv reac: dry mouth, drowsiness, mimic dehydration symptoms
Don’t use in glaucoma, intestinal/urinary tract blockage

Question 5

Hormones for treating prostate and breast cancer

Answer 5

megestrol (Megace), goserelin (Zoladex)
It’s not a cure!
Only slows the growth of cancer

Question 6

UTI treatment

Answer 6

Amoxicillin, trimethoprim (Bactrim), sulfamethoxazole (Septra), nitrofurantoin (Macrodantin) (bacteriostatic: decrease growth of bacteria, can upset GI so take with food!).
Need culture and sensitivity before treating to very what the infection is susceptible to and resistant to!
Urinary analgesics: phenazopyridine (Pyridium) - OTC med, anesthetic, should not be used > 2 days! Urine will be orange brown color with this.
Herbal considerations: cranberry inhibits bacteria from sticking to walls of bladder