Cholinergic Drugs

Question 1

Which nervous system do cholinergic drugs affect?

Answer 1

Parasympathetic nervous system

Question 2

What is parasympathetic nervous system in charge of?

Answer 2

Rest and digest

Question 3

What do acetylcholine (Ach) do?

Answer 3

Send messages from nerve cells to other cells in the body

Question 4

What are the Ach receptors and what do they do?

Answer 4

Muscarinic receptors: stimulate smooth muscle
Nicotinic receptors: stimulate skeletal muscle

Question 5

What caused Alzheimer’s?

Answer 5

Dysfunction of Ach

Question 6

What do acetylcholinsterase (AchE) do?

Answer 6

Inactivate Ach, so it’s used to treat Alzheimer’s

Question 7

Cholinergic crisis cause and s/s

Answer 7

Caused by overdoes.
S/s include NVD, bradycardia, hypotension, stomach pain, resp depression

Question 8

Cholinergic drugs interact with what class of drugs?

Answer 8

Aminoglycoside (a class of antibiotics), corticosteroids, and other cholinergics (b/c of high risk of toxicity)

Question 9

What is atropine and what does it do?

Answer 9

Antimuscarinic, cholinergic blocking, increase hr, dilate pupil, decrease urine

Question 10

Antidote of cholinergic drugs

Answer 10

Atropine!