Pulmonary Conditions & Tobacco cessation: COPD

Question 1

people with what deficiency are at higher risk of developing COPD?

Answer 1

AAT = alpha 1 antitrypsin deficiency

Question 2

Post-bronchodilator FEV1/FVC of what confirms COPD?

Answer 2

< 0.70

Question 3

GOLD system COPD

Answer 3

stages 1-4

used to assess prognosis and disease progession

Question 4

GOLD 1

Answer 4

Mild
FEV1 > 80%

Question 5

GOLD 2

Answer 5

Moderate
50% - 80% FEV

Question 6

GOLD 3

Answer 6

Severe
30% - 50% FEV

Question 7

GOLD 4

Answer 7

Very severe
< 30% FEV

Question 8

Most common scoring systems for COPD

Answer 8

mMRC
CAT

Question 9

What is COPD exacerbation

Answer 9

increase in respiratory symptoms that worsen over < 14 days

Question 10

How many exacerbations per year are considered frequent?

Answer 10

2

Question 11

ICS is recommended in patients with,….

Answer 11

Eosinophil count > 300
and history of exacerbations

Question 12

ICS is not recommended in patients with

Answer 12

Eosinophil count < 100

Question 13

CAT score > 10, mMRC > 2 then…

Answer 13

group B

Question 14

CAT score < 10, mMRC < 0-1 then….

Answer 14

Group A

Question 15

> 2 moderate exacerbations or > 1 leading to hospitalization then…

Answer 15

Group E

Question 16

Group A initial treatment

Answer 16

Bronchodilator

SAMA PRN, SABA PRN, LAMA or LABA

Question 17

Group B initial treatment

Answer 17

LAMA + LABA

Question 18

Group E initial treatment

Answer 18

LAMA + LABA

+ ICS if eosinophils > 300

Question 19

When should antibiotics be used?

Answer 19

if increased sputum purulence, volume or dyspnea, or if on technical ventilation

Question 20

SAMA (short acting muscarinic antagonists) drugs

Answer 20

Ipratropium = Atrovent

Question 21

SAMA & LAMA side effects

Answer 21

Dry mouth
Cough
Bitter Taste

Question 22

SAMA & LAMA warnings

Answer 22

caution in pts with narrow angle glaucoma, myasthenia graves, urinary retention, mph and bladder neck obstruction

Question 23

LAMA (long muascarinic antagonists) drugs

Answer 23

Tiotropium = Spiriva
umeclidinium = incruse ellipta

Question 24

LABA can be used as mono therapy in which disease state?

Answer 24

COPD

Question 25

For ICS containing LABA, it is important to

Answer 25

rinse mouth after use to prevent candidiasis

Question 26

Roflumilast CI

Answer 26

moderate to severe liver impairment

Question 27

Roflumilast side effects

Answer 27

Diarrhea
weight los
nausea
dec appetite
insomnia
HA