Male & Female Health: Benign Prostatic Hyperplasia (BPH) Flashcards
Signs and symptoms of BPH
Hesitancy, intermittent urine flow, strain or weak stream
urinary urgency and leaking/dribbling
urinary frequency, especially at night
incomplete emptying of bladder
5 alpha-reductase inhibitors should not be used in..
men who have bladder outlet obstruction symptoms without prostate enlargement
5 alpha-reductase inhibitor works by…
reducing prostate size
take awhile to work
1st line treatment for BPH?
alpha-1 blockers
Alpha-1 blockers mechanism
cause relaxation of smooth muscle in the prostate and bladder neck
reduces bladder outlet obstruction and improve urinary flow
Non-selective vs selective alpha blockers
Non-selective = more side effects = terazosin, doxazosin
selective = tamsulosin, alfuzosin, silodosin
If cataract surgery is planned, then txm with alpha blockers should be…
delayed, risk of developing intraoperative floppy iris syndrome
Alpha blocker warnings
Orthostatic hypotension/syncope
intraoperative floppy iris syndrome (IFIS)
Alpha blocker side effects
dizziness
fatigue
headache
abnormal ejaculation
When are non-selective alpha blockers given
usually at bedtime
5- alpha reductase inhibitors
Finasteride
Dutasteride
5 alpha reductase inhibitor CI
women of child bearing potential
pregnancy
children
5 alpha reductase inhibitor side effects
impotence
dec libido
ejaculation issues
breast enlargement and tenderness
sexual SE decrease over time in some men
5 alpha reductase inhibitor notes
pregnant women shouldn’t handle or take these
treatment for 6 months+ may be req for maximal efficacy
will shrink prostate and decrease PSA lvls