Pulmonary circulation Flashcards

1
Q

What are the main mechanisms of sustained pulmonary arterial hypertension?

A

Persistent hypoxic vasoconstriction and the associated vascular structural remodeling

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2
Q

Where is blood flow greatest in the lungs?

A

Base

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3
Q

How is interstitial fluid pressure in the lungs compared to that in the peripheral subcutaneous tissue?

A

Interstitial fluid pressure in the lungs is slightly more negative

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4
Q

What is the normal value for V/Q (ventilation / perfusion)?

A

0.8

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5
Q

How does the V/Q RATIO increase within the lung?

A

Increases base to apex (more mismatch at apex)

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6
Q

Would conducting bronchioles have a high or low V/Q ratio?

A

Low V/Q (very little ventilation compared to a lot of blood flow)

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