Cerebellar function Flashcards

1
Q

definition: titubation

A

tremor of the entire trunk or head during stance and gait, caused by cerebellar midline lesions

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2
Q

which cell type of the source of axons leaving the cerebellar cortex?

A

purkinje

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3
Q

which cerebellar cortex cell makes excitatory synapses?

A

granule

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4
Q

what is the effect of mossy fibers on purkinje cells?

A

excitatory (via granule cells)

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5
Q

what is the effect of climbing fibers on purkinje cells?

A

excitatory

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6
Q

deficiency of which vitamin is associated with atrophy of the anterior lobe of the cerebellum?

A

thiamine

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7
Q

which part of the cerebellum is responsible for verb generation?

A

right lateral cerebellum

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8
Q

what is the origin of the mossy fibers?

A

spinal cord and brainstem

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9
Q

what is the origin of the climbing fibers?

A

inferior olivary nucleus

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10
Q

what is the effect of purkinje cells on deep cerebellar nuclei?

A

inhibitory

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11
Q

what is the output effect of the deep cerebellar nuclei?

A

excitatory

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12
Q

what is the role of golgi cells?

A

cerebellar cortex cells that affect dendritic input to purkinje cells by inhibiting granule cells

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13
Q

what is the role of stellate cells?

A

cerebellar cortex cells that affect dendritic integration of purkinje cells through inhibitory synapses onto dendritic tree

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14
Q

what is the role of basket cells?

A

cerebellar cortex cells that make inhibitory synapses near initial segment of purkinje cell axon

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15
Q

what is the anatomical location of the vestibulocerebellum?

A

flocculonodular node

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16
Q

what are the functions of the vestibulocerebellum?

A
  1. regulate equilibrium 2. regulate gait and posture through vestibulospinal reflexes 3. control of eye movements and coordinate movement of head and eyes 4. visual guidance of movement
17
Q

what are the main functions of the spinocerebellum - vermis portion?

A
  1. regulate axial and proximal musculature 2. ongoing motor execution 3. regulation of muscle tone
18
Q

what are effects of lesions to the vestibulocerebellum?

A
  1. ataxic gait 2. cerebellar nystagmus 3. deficits in smooth pursuit eye movements
19
Q

what are the main functions of the spinocerebellum - paravermal region?

A
  1. regulation of distal muscles 2. ongoing motor execution 3. regulation of muscle tone
20
Q

what are the effects of lesions to the spinocerebellum?

A
  1. ipsilateral hypotonia 2. dysmetria 3. intention tremor 4. pendular reflexes
21
Q

what are the functions of the cerebrocerebellum?

A
  1. preparation of movement 2. learned, skilled, voluntary movement 3. timing functions
22
Q

what are the effects of lesions to the cerebrocerebellum?

A
  1. delays in initiating and terminating movements 2. problems with multi joint movements 3. inability to judge elapsed time in non-motor tasks
23
Q

definition: dysarthria

A

disorder in articulating speech