Cerebellar function Flashcards
definition: titubation
tremor of the entire trunk or head during stance and gait, caused by cerebellar midline lesions
which cell type of the source of axons leaving the cerebellar cortex?
purkinje
which cerebellar cortex cell makes excitatory synapses?
granule
what is the effect of mossy fibers on purkinje cells?
excitatory (via granule cells)
what is the effect of climbing fibers on purkinje cells?
excitatory
deficiency of which vitamin is associated with atrophy of the anterior lobe of the cerebellum?
thiamine
which part of the cerebellum is responsible for verb generation?
right lateral cerebellum
what is the origin of the mossy fibers?
spinal cord and brainstem
what is the origin of the climbing fibers?
inferior olivary nucleus
what is the effect of purkinje cells on deep cerebellar nuclei?
inhibitory
what is the output effect of the deep cerebellar nuclei?
excitatory
what is the role of golgi cells?
cerebellar cortex cells that affect dendritic input to purkinje cells by inhibiting granule cells
what is the role of stellate cells?
cerebellar cortex cells that affect dendritic integration of purkinje cells through inhibitory synapses onto dendritic tree
what is the role of basket cells?
cerebellar cortex cells that make inhibitory synapses near initial segment of purkinje cell axon
what is the anatomical location of the vestibulocerebellum?
flocculonodular node
what are the functions of the vestibulocerebellum?
- regulate equilibrium 2. regulate gait and posture through vestibulospinal reflexes 3. control of eye movements and coordinate movement of head and eyes 4. visual guidance of movement
what are the main functions of the spinocerebellum - vermis portion?
- regulate axial and proximal musculature 2. ongoing motor execution 3. regulation of muscle tone
what are effects of lesions to the vestibulocerebellum?
- ataxic gait 2. cerebellar nystagmus 3. deficits in smooth pursuit eye movements
what are the main functions of the spinocerebellum - paravermal region?
- regulation of distal muscles 2. ongoing motor execution 3. regulation of muscle tone
what are the effects of lesions to the spinocerebellum?
- ipsilateral hypotonia 2. dysmetria 3. intention tremor 4. pendular reflexes
what are the functions of the cerebrocerebellum?
- preparation of movement 2. learned, skilled, voluntary movement 3. timing functions
what are the effects of lesions to the cerebrocerebellum?
- delays in initiating and terminating movements 2. problems with multi joint movements 3. inability to judge elapsed time in non-motor tasks
definition: dysarthria
disorder in articulating speech
