Liver and gall bladder

Question 1

what are the components of phase I of hepatic biotransformation?

Answer 1

oxidation, reduction, hydrolysis

Question 2

what are the components of phase II of hepatic biotransformation?

Answer 2

glucoronidation, sulfation, acetylation

Question 3

what is the goal of phase I of hepatic biotransformation?

Answer 3

expose a functional group, make compound more polar (water soluble) and suitable for phase II reactions

Question 4

what is the goal of phase II of hepatic biotransformation?

Answer 4

increase hydrophilicity by making compound larger, bulkier, more water soluble

Question 5

bile acids are synthesized from what compound?

Answer 5

cholesterol

Question 6

what part of the GI tract facilitates enterohepatic circulation of bile acids and bile salts?

Answer 6

ileum

Question 7

what is the function of somatostatin on the gall bladder?

Answer 7

inhibition

Question 8

what is the function of somatostatin on the sphincter of Oddi?

Answer 8

inhibition