Pulmonary Flashcards
Short Acting B2 Agonists
SABA
drug of choice for quick relief of asthma attack
rescue inhaler
5-15 min onset, lasts 4-6 hours
Examples of SABAs
albuterol
Long Acting B2 Agonists
LABA
adjunct to SABAs
1 hr onset, lasts 12 hrs
Examples of LABAs
salmeterol
MOA of SABAs and LABAs
relax bronchial smooth muscle by acting on B2 receptors
SE of SABAs and LABAs
skeletal muscle tremor, cardiac stimulations on excessive doses
Inhaled Corticosteroids
example and use
Fluticasone
for acute attacks
Systemic Corticosteroids
example and use
prednisolone, prednisone
prevent attacks
Use of Corticosteroids
controller medication for persistent attacks
MoA of Corticosteroids
act on glucocorticoid receptors and stimulate protein synthesis
anti-inflammatory
takes 4-12 hrs to work
Benefits of Corticosteroids
inhibit inflammation at all levels
reduce mucous production
increase B2 receptor levels
SE of Inhaled Corticosteroids
thrush / candidiasis
use spacer to get more to lungs; rinse out mouth after use
Example of Long Acting Muscarinic Antagonist
LAMA
tiotropium
Use of SAMA and LAMA
COPD
SE of SAMA and LAMA
sympathetic effects
