Pulmonary 4 Flashcards
What is the treatment for active TB?
Rifampin, isoniazid, pyrazinamide, Ethambutol for 2 months. Then, Rifampin and isoniazid for 4 mo. 6 mo total.
Rifampin SE.
Thrombocytopenia, orange colored secretions.
Isoniazid SE.
Hepatitis, peripheral neuropathy. Take pyridoxine B6 to prevent the neuropathy.
Pyrazinamide SE.
Hepatitis and hyperuricemia, photosensitive dermatologic rash.
Ethambutol SE.
Optic neuritis, peripheral neuropathy.
Streptomycin SE.
Ototoxicity, nephrotoxicity.
GI tract mc sight of these tumors, may secrete serotonin, ACTH, ADH, or melanocyte stimulating hormone.
Bronchial carcinoid tumors.
Periodic episodes of diarrhea, flushing, tachycardia, and bronchoconstriction.
Carcinoid syndrome.
MC cause of cancer-related deaths in the US.
RF of smoking and asbestosis exposure.
Bronchogenic carcinoma
How is non-small cell bronchogenic carcinoma treated?
Surgical resection
How is small cell bronchogenic carcinoma treated?
Due to metastasis being common at presentation, treatment is usually chemotherapy.
Who gets a low dose CT screening for lung CA.
55-80 who have a 30 PPY smoking hx and who currently smoke or have quit within 15 years.
MC primary lung CA in smokers, women, men, and non smokers.
This cancer is typically peripheral, histology gland formation, mucin production.
Adenocarcinoma
How is squamous cell lung carcinoma different from small cell?
Cavitary lesions, hyper calcemia and Pancoast syndrome.
Both are centrally located.
Antibodies against presynaptic voltage-gated calcium channels. MC associated with small cell lung cancer.
Proximal muscle weakness that improves with repeated muscle use.
Dry mouth most common, hyporeflexia.
Lambert-eaton Myasthenic syndrome.
