pt 6 (mouse) Flashcards
what is the genus of mouse
mus musculus
describe 5 strains of mice commonly used in research and name characteristics
white swiss
C57 - agressive
hairless - have eyelashes
nude - athymic have no t-cells
SCID - no t- or b-cells
describe the estrus cycle, gestation, and weaning age of a mouse
estrus cycle - 5 days
gestation - 19 days
weaning - 21 days
are mice altricious or precocious? and what do those terms mean?
altricious - babies need a lot of care
lee-boot effect
females are housed in groups synchronize estrus cycles; absence of male pheromones lead to anestrus
whitten effect
female can be induced into estrus by exposure to male mouse urine
bruce effect
pregnant females exposed to a strange male during the first four days of gestation will block the first pregnancy, reovulate
how can you tell a female mouse has been bred?
a vaginal plug stays in the vagina 12 hours after mating
a mouse is bred on postpartum heat, what is the effect of this?
delayed implantation occurs and increases gestation period 25-30 days
what is the term used to describe the time of day when mice are most active?
crepuscular - twilight to dawn
what causes ringtail and what are the symptoms?
improper humidity; annular constrictions on the tail leading to necrosis and sloughing
what is barbering and how is it treated?
when mice chew the hair off of their cage mates; separate the mice
what etiologic agent causes LCM? signs and treatment?
virus; acute death, hunched, rough coat, emaciated; no treatment - prevent by disease-free breeding stock
what is another name for mouse typhoid? signs and treatment?
salmonellosis; diarrhea and many are diagnosed by fecal cultures; eliminate infected animals
what is a disease other than salmonellosis that causes diarrhea in mice?
tyzzer’s disease
how is tyzzer’s disease diagnosed on necropsy?
liver lesions
what are the symptoms of respiratory disease in mice? 3 common etiological signs?
chattering, weight loss, unthrifty appearance, head-tilt or circling; mycoplasma, sendai virus, pneumonic virus of mice
3 possible treatments for an outbreak of respiratory disease in a room full of mice?
antibiotics, let disease run its course, or depopulate
name a zoonotic disease one can contract from mice
lymphocytic choriomeningitis virus
what ectoparasites are common in mice?
fur mites
polyplax lice
demodectic mange
name 2 endoparasites of mice that you might see on fecal float - should you also do a direct smear? describe procedure
pinworm and tapeworm;
what are the 2 pinworm species commonly found in mice?
syphacia and aspicularis
