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vtt 214 - lab animal > lecture quiz 2 > Flashcards

lecture quiz 2 Flashcards

1
Q

strains of mice commonly used in research and characteristics

A

white swiss - albino
C57 - very aggressive, black and brown
hairless - with eyelashes
nude - no t-cells, no whiskers
SCID - no t- or b-cells

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2
Q

strains of rats commonly used in research and characteristics

A

sprague-dawley - white albino, outbred
Lewis - white albino, inbred
long-evens (hooded) - black and white, aggressive

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3
Q

ringtail

A

from improper humidity; annular constrictions on the tail leading to necrosis and sloughing

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4
Q

barbering

A

chew hair of head of cage mates

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5
Q

chromodacryorrhea

A
  • red tears
  • symptom not disease
  • harderian gland secretes pigments
  • causes: stress, respiratory diseases, or SDAV
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6
Q

mammary tumors

A

common; bengin

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7
Q

lymphocytic choriomeningitis virus

A
  • mice
  • cause: virus
  • zoonotic
  • symptoms: acute death, hunched, rough coat, emaciated
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8
Q

salmonellosis

A
  • mouse typhoid
  • cause: bacteria
  • symptoms: diarrhea
  • treatment: eliminate infected animals
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9
Q

tyzzer’s disease

A
  • cause: fecal-oral transmission of spores
  • symptoms: rough coat, watery yellow diarrhea, death, liver lesions
  • treatment: antibiotics to treat but doesn’t usually work - euthanize
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10
Q

respiratory diseases

A
  • cause: mycoplasma. sendai virus, PVM
  • symptoms: weight loss, chattering, head-tilt, unthrifty appearance
  • treatment: antibiotics, let disease run its course, or depopulate
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11
Q

dermatomycosis

A
  • ringworm
  • causes: microsporum and trichophyton
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12
Q

sialodacryoadenitis

A
  • cause: virus through direct contact
  • symptoms: eye squinting, swelling on neck and jaw, protrusion of eye, keratitis, red tears, salivary and lacrimal glad inflammation
  • treatment: ointment for keratitis but no treatment
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13
Q

what antibiotics can be used on rodents and why they are used

A

many disrupt normal GI function- don’t use narrow spectrum antibiotics

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14
Q

how to tell if a mouse has been bred

A

vaginal plug

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15
Q

polyestrous vs seasonally polyestrous

A

multiple cycles a year; multiple cycles per breeding season

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16
Q

decimal system for recording gender

A

M.F.U (males, females, unknown)

17
Q

mouse reproduction

A

breeding: 60 days
estrus: 5 days
gestation: 19 days
weaning: 21 days
altricious

18
Q

rat reproduction

A

breeding: 100 days
estrus: 5 days
gestation: 21 days
weaning: 21 days
altricious

19
Q

lee-boot effect

A

females are housed in groups synchronize estrus cycles; absence of male pheromones lead to anestrus

20
Q

whitten effect

A

female can be induced into estrus by exposure to male mouse urine

21
Q

bruce effect

A

pregnant females exposed to a strange male during the first four days of gestation will block the first pregnancy, reovulate

22
Q

colony

A

all animal population maintained under some degree of control for the purpose of reproduction

23
Q

closed colony

A

a colony that is maintained without the introduction of animals from other sources

24
Q

strain

A

a group of animals of known ancestry maintained by a deliberate mating system; generally with some distinguishing characteristics

25
Q

inbred strain

A

mating brother and sister for 20 or more consecutive generations; also parent and offspring

26
Q

phenotype vs genotype

A

physical, biochemical and physiological makeup of an individual vs the genetic constitution of an individual

27
Q

meiosis

A

cell division occurring in sex cells where each cell receives half the number of chromosomes

28
Q

mitosis

A

cell division occurring in somatic cells where each cell receives a full complement of chromosomes

29
Q

pheromone

A

a substance secreted in urine, sweat, or glandular secretions and perceived by another individual of the same species releasing specific reaction on behavior

30
Q

gnotobiology

A

study of animals raised in the absence of microorganisms or in the presence of known microbial strains or communities

31
Q

conventional animal

A

animals raised under standard conditions

32
Q

SPF animal

A

May harbor disease-causing microbes, but not a particular one

33
Q

axenic animal

A

animal that is free of all known microorganisms and parasites

34
Q

pathogen free animal

A

Has no disease-causing microbes but may have other microbes

35
Q

gnotobiotic animal

A

all microbes known; starts as axenic and inoculated with certain microorganisms

36
Q

COBS

A
  • Born by Caesarean section
  • Maintained in sterile environment
  • Fed sterile food
  • Kept in sterile isolators with sterile bedding
37
Q

transgenic animal

A

an animal that carries a foreign gene that has been deliberately inserted into its genome; knockout animal

vtt 214 - lab animal (33 decks)

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