Prostate Cancer (Exam 2) Flashcards
When does Prostate Cancer Incidence Increase?
Incidence Increase rapidly after 50:
-80% of all cases in men >65 yrs of ager
Controversy with prostate cancer
Prostate cancer is among most common cancer in men
Many cases of prostate cancer never become relevant
Most prostate cancers grow slowly so men die of other causes
PSA screening was widely adopted before we had evidence for supporting its use
Prostate Cancer: Health Promotion
Start at age of 50 years and have discussion
Men at higher risk start at 45
What men are at higher risk of prostate cancer?
First degree relatives with cancer before 65 years old and african americans
Prostate cancer screening involves
PSA
with or without
DRE
Prostate Cancer: Early Stage Treatment
Watchful waiting
Repeated digital rectal exam and PSA follow up
Prostate Cancer Surgical Treatment
Radical Prostatectomy
Prostate removed
Adverse Outcomes of Radical Prostatectomy
Erectile dysfunction (tends to return of 24 months)
Urinary incontinence (tends to return normal in a few months)
Prostate Cancer: Radiation Therapy
Used alone or in combination with surgery
External (teletherapy) or internal (brachytherapy)
Brachytherapy of prostate cancer
Seeds are implemented into prostate
Prostate Cancer Drug Therapy
Androgen deprivation therapy
Chemotherapy for metastasis