Principle Systems Pt. 1 (Skin, Nervous, Endocrine, Lymphatic) Flashcards
Function of skin?
Regulates body temperature, protects, and receives stimuli
Function of nervous system?
Receives and transmits nerve impulses
Function of endocrine system?
Transports hormones through the blood
Function of lymphatic system?
Protects against disease
Function of digestive system?
Breaks down food for use by the body and eliminates waste
Function of the cardiovascular system?
Distributes oxygen to the cells
Function of the respiratory system?
Supplies oxygen
Function of the skeletal system?
Supports and protects the body and aids body movement
Function of the muscular system?
Brings about movement and maintains posture
Function of the urinary system?
Regulates fluids
Function of the reproductive system?
Reproduces the organism
Dermatology
Study of the skin
Another name for the skin as an organ
Integumentary system
The two root words for skin?
Dermat/ cutane
Subcutaneous layer
Attaches the skin to underlying structures
Epidermis
Outer layer of skin
Dermis
Vascular layer of skin (between epidermis and subcutaneous)
Melanin
Dark pigment
Carotene
Yellow-orange skin pigment found in people of Asian origin
Which skin layer gives rise to basal cell carcinoma?
Basal or germinative layer
Sebum
Oily substance which keeps hair from drying out and inhibits bacteria growth
What does sebum form when it accumulates?
Blackheads
Medical term for blackheads
Comedone
Sebaceous glands
Oil glands which secrete sebum
What do sudoriferous glands produce?
Sweat
Where would you find the apocrine glands?
Armpits
Where would you find eccrine glands?
All over the skin, except lips (cheil/o) and nails (onych/o)
What do the ceruminous glands do?
Produce earwax
What are the 4 main kinds of touch?
Light touch, continuous pressure, heat/cold, pain
What is a burn?
Tissue damage caused by excessive heat, ultraviolet radiation or corrosive chemicals
1st degree burn
Involves the epidermis
2nd degree burn
Involves the epidermis and dermis
3rd degree burn
Destroys the epidermis, dermis and organs
Acanthosis
Thickening of the skin
Acne rosacea
Skin disease due to thinning of the skin- acne like spots
Acne vulgaris
Skin disease of the sebaceous glands causing papules (red spots)
Bullae
Large fluid-containing blisters
Cellulitis
Inflammation of the subcutaneous layer of the skin
Chancre
Ulcer-type sore associated with syphilis
Dermoid cyst
Cyst present at birth–contains embryonic material
DLE
Disseminated lupus erythematosus (spreads to destroy vital tissues)
Erosion
Rubbing away of tissue
Excoriation
Injury worsened by scratching/ friction
Fissure
A cleft or split
Haemangioma
Birth mark (port wine stain type)
Herpes simplex
Virus causes skin infection - cold sores
Herpes zoster
Shingles skin infection due to chicken pox virus
Hidr/o
Sweat
Impetigo
Acute and contagious disease–pustules and scabs
Kerat/o
Root for scaly/horny
Lesion
Abnormal change in tissue
Lupus erythematosus
Inflammatory dermatitis- ‘butterfly lesions’ over nose and cheeks
Macule
Spot or discolouration not raised above the skin- measles rash
Naevus
Birth mark
Nodule
Small node
Papilloma
Simple tumour- not malignant
Papule
Spot- small, raised and solid
Paronychia
Infection of the nail bed (whitlow)
Percutaneous
Through the skin
Pil/o, trich/o
Hair
SLE
Systemic lupus erythematosus- spreads to destroy vital tissues
CNS
Central nervous system
PNS
Peripheral nervous system
ANS
Autonomic nervous system
Neurology
Study of disorders of the functions and disorders of the nervous system
Four main parts of the brain?
Cerebrum/ cortex, cerebellum, diencephalon, brain stem
Main lobes of the cerebrum
Frontal, parietal, temporal and occipital
What does the cerebellum do?
Co-ordinate skeletal muscles and maintains muscle tone
What does the diencephalon do?
Controls pain, temperature, touch and pressure, as well as being responsible for our emotions
What does the brain stem do?
Connects the brain to the spinal cord
What are the 4 regions of the spinal cord?
Cervical, thoracic, lumbar, sacral
Grey matter
Cranial nerve cells
White matter
The myelin sheath around cranial cells
Schwann cells
Cells that make up a myelin sheath
What are the 4 parts of a nerve cell?
Nucleus, cytoplasm, dendrite/tree, axon
What does cytoplasm do in a nerve cell?
Surrounds the nucleus
What does the dendrite/tree do in a nerve cell?
Receives impulses and connects up the parts of the cell
What does the axon do in a nerve cell?
Conducts impulses away from the cell body
Neurone
Basic structural nerve cell
Neuroglia
Supporting nerve cells that stick to the neuron and the synapse (glia= glue)
Synapse
The gap between two neurons
Neuron
Nerve cell that carries electrical impulses
Meninges
Protective membrane of the brain and spinal cord
Cerebrospinal fluid
Protective fluid layer of brain and spinal cord
What are the 3 layers, and 2 spaces in between, of the meninges?
Dura mater (hard outer layer), epidural space, arachnoid mater (vascular layer), subarachnoid space, pia mater (soft inner layer)
Akathisia
Inability to sit still (restlessness)
Alzheimer’s
Disease caused by destruction of neurones
Aphasia
Inability to speak (caused by brain damage)
Ataxia
Uncoordinated gait when walking
Babinski’s
A sign of reflex of toe upwards instead of down- nervous system damage
Bell’s palsy
Paralysis of facial muscles due to injury or cranial nerve disease
BSE
Bovine spongiform encephalopathy (mad cow disease)
CJD
Creutzfeldt-Jacob disease (fatal degenerative brain disorder)
CVA
Cerebrovascular accident or stroke- ruptured or blocked blood vessels
Dysarthria
Difficulty in articulation of speech due to nerve damage
Hydrocephaly
Excessive cerebrospinal fluid due to circulation damage- water on the brain
Idio
Peculiar to the individual
Kinesis
Movement
Microcephaly
Abnormally small head
MND
Motor neurone disease- progressive damage to parts of the nervous system
Narcolepsy
Compulsive sleeping at any time
Poli/o
Grey matter
Somatic
Pertaining to the body
TENS
Transcutaneous Electrical Nerve Stimulation
TIA
Transient Ischaemic Attack- insufficient blood supply to the brain
Cerebral angiogram
X-ray of the blood vessels of the brain using an opaque medium
Craniotomy
Cutting into the cranium to relieve pressure
EEG
Electroencephalogram- records electrical activity of the brain
Intrathecal
Injection directly into the meninges
Lumbar puncture
Withdrawal of spinal fluid from the meninges of the spinal cord
Meningitis
Inflammation of the meninges
Lepto-
Thin
Leptomeningitis
Inflammation of the pia mater and arachnoid membrane
Pachy-
Thick
Pachymeningitis
Inflammation of the dura mater
Meningococcal meningitis
Inflammation of the meninges caused by bacteria (coccus)
Coccus
Bacteria
Hormones
Chemical messengers
Endocrine glands
Ductless glands which allow hormones to be released directly into the bloodstream
What are the 6 main types of endocrine gland?
Pituitary, thyroid, parathyroid, adrenal, pineal, thymus
What do exocrine glands do?
Glands with ducts that release secretions
What are the 3 main types of exocrine gland?
Merocrine, apocrine, holocrine
What do the merocrine glands do?
Release saliva
What do the holocrine glands do?
Sebaceous/ oil releasing glands
Hypothalamus
Part of the brain that controls aggression and rage, regulates food and drink intake, and maintains consciousness and sleep patterns
How does the hypothalamus work?
Receives messages from nerve cells, which then triggers a response from the pituitary gland
The 2 parts of the pituitary gland
Anterior and posterior
The 6 anterior pituitary gland hormones
HGH, TSH, ACTH, FSH, LH, PRL
The 2 posterior pituitary gland hormones
ADH, Oxytocin
HGH
Human Growth Hormone (carbohydrate control)
TSH
Thyroid Stimulating Hormone (controls the thyroid gland)
ACTH
Adrenocorticotrophic Hormone (stimulates the adrenal cortex)
FSH
Follicle Stimulating Hormone (acts on the reproductive system)
LH
Luteinising Hormone (acts on the reproductive system)
PRL
Prolactin (stimulates production of milk)
ADH
Antidiuretic Hormone (controls water in the body by acting on the kidneys)
Oxytocin
Causes the uterus to contract, starting labour and milk production
Acromegaly
Oversecretion of HGH
Diabetes insipidus
Under secretion of ADH
Dwarfism
Under secretion of HGH during growth years
Gigantism
Over secretion of HGH during the growth years
Main function of the thyroid gland
Manufacturing thyroxine (atoms of iodine) as well as calcitonin (calcium and phosphate in the blood)
Thyroxine
Hormone which plays a crucial part in the function of almost all the body’s systems
Calcitonin
Controls calcium levels in the blood
Cretinism
Under secretion of thyroid hormones in a foetus, or in infancy
Exopthalmos
Over secretion of thyroid hormones making the eyes protrude
Goitre
Over secretion of thyroid hormones, enlarging the thyroid gland
Myxoedema
Under active thyroid gland causing swelling of facial tissues
What is the function of the parathyroid glands?
Control calcium levels by releasing PTH (Parathyroid Hormone). Also helps control levels of phosphate and vitamin D
Hypoparathyroidism
Deficiency of PTH
Tetany
Deficiency of calcium
Tests to measure for thyroxine
T3 and T4
Two parts of the adrenal glands
Cortex and medulla
The 5 adrenal gland hormones
Cortisone, aldosterone, gonadocorticoids, adrenaline, noradrenaline
Cortisone
Controls the use of glucose
Aldosterone
Controls blood pressure and salt balance
Gonadocorticoids
Sex hormones (steroids)
Adrenaline
Prepares the body for action
Noradrenaline
Maintains an even blood pressure
Cushing’s Syndrome
Over secretion of cortisone
Addison’s Disease
Under secretion of aldosterone
Virilism/ masculinisation
Excess male sex hormone produced
What does the pineal gland produce?
Melatonin (skin pigment)
Function of the thymus gland
Helps induce the production of antibodies and releases thymosin and thymopoietin
Thymosin
Stimulates the development of T cells (plays a central role in immune response)
Thymopoietin
Hormone which affects the rate at which your skin ages
Which 2 hormones do the ovaries produce?
Oestrogen and progesterone
Which hormone do the testes produce?
Testosterone
Which organ is both an endocrine and exocrine gland?
Pancreas
What are the two functions of the pancreas (respectively as an endocrine, and an exocrine gland)?
Endocrine= secretes insulin Exocrine= secretes it into the gastro-intestinal tract
What are the three key symptoms of diabetes mellitus?
Polyuria, polydipsia, polyphagia
Polyuria
Increased urination
Polydipsia
Excessive thirst
Polyphagia
Excessive eating
IDDM (insulin dependent diabetes mellitus)
Type I Diabetes
NIDDM (non insulin dependent diabetes mellitus)
Type II Diabetes
Type I Diabetes
Early onset diabetes requiring insulin, patients are known as insulin dependent
Type II Diabetes
Late onset and much more common than Type I Diabetes. Normally occurs in people over 40 and overweight. The symptoms can be controlled by diet, exercise and/ or medication
Hypoglycaemia
Too much insulin is administered or a meal is skipped- insufficient glucose
Hyperglycaemia
Too little insulin causes excess glucose
Long-term complications of unmanaged diabetes
Heart and blood vessel diseases, kidney disease, diseases of the nerves and diseases of the eyes
Immunology
Study of the immune system
What is the lymphatic system made up of?
A network of lymphatic vessels that carry lymph towards the heart
Lymph
Clear liquid containing white blood cells
Metastasis
When cancer spreads via the lymphatic system to other areas of the body
Lymph duct
Large lymph vessel that empties lymph into a subclavian vein
Subclavian vein
Large blood vessel in the neck- a deep vein
What are the two lymph ducts called?
Right duct, thoracic duct
Antigens
Chemicals foreign to the body
Pathogens
Contain antigens
Human Autoimmune Disease
When the immune system mistakenly recognises its own tissues and chemicals as foreign bodies
RA
Rheumatoid arthritis
Rheumatoid arthritis
Human Autoimmune disease that causes pain, swelling and stiffness in the joints
Systemic Lupus Erythematosus
Human Autoimmune Disease causing inflammation in the joints, skin and other organs
Rheumatic Fever
Human Autoimmune Disease. Rare complication from a bacterial throat infection. Causes painful joints and heart problems.
Hemolytic anaemia
Anaemia due to haemolysis, the abnormal breakdown of RBCs, in blood vessels or other parts of the body (usually the spleen)
Pernicious anaemia
Condition where the body can’t make enough healthy RBCs because it doesn’t have enough vitamin B12
Graves’ Disease
Human Autoimmune Disease. Also known as toxic diffuse goiter, it frequently results in hyperthyroidism and an enlarged thyroid.
Multiple Sclerosis (MS)
Human Autoimmune Disease. Affects the brain and spinal cord with varying severity.
Adenitis
Inflammation of a gland
AIDS
Acquired Immune Deficiency Syndrome
Allergies
Overreaction to an antigen (produces immunity)
Anasarca
Widespread oedema (the fluid in tissues doesn’t drain back)
Ascites
Free fluid in the peritoneal cavity
HIV
Human Immunodefiency Virus
Hodgkin’s Disease
A form of cancer of the lymphatic system caused by a virus
Lymohangi/o
Lymph vessels
Lymphocythaemia
Excessive lymphocytes in the blood
Lymphocyte
Small form of leucocyte with a single round nucleus, occurring especially in the lymphatic system
Lymphocytopenia
Deficiency of lymphocytes in the blood
Mononucleosis
Infectious disease (glandular fever)
Paracentesis
Drawing off of fluid
Splenomegaly
Abnormal enlargement of the spleen
Thoracocentesis
Drawing off of fluid from the chest