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Conditions: GI > Primary Biliary Cirrhosis > Flashcards

Primary Biliary Cirrhosis Flashcards

1
Q

What is primary biliary cirrhosis?

A

Autoimmune granulomatous inflammation leading to damaged intralobular bile ducts

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2
Q

What causes primary biliary cirrhosis?

A

Autoimmune

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3
Q

Symptoms?

A

Cholestasis leading to jaundice

Portal hypertension
- Varices

Diarrhoea

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4
Q

Signs?

A

Hepatomegaly

Splenomegaly

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5
Q

Tests?

A

LFTs

USS
ERCP - rule out DDx’s of painless obstructive jaundice

Liver biopsy - granulomatous inflammation

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6
Q

LFT findings?

A

Everything raised

Albumin and INR down in chronic cases

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7
Q

Surgery?

A

Liver transplant

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8
Q

Pharma treatments?

A

Pruritis - Colestyramine

Diarrhoea
- Codeine phosphate

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9
Q

What prophylacting treatment is needed in conditions where bile can’t enter the duodenum?

A

fat soluble vitamin supplements

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Conditions: GI (36 decks)

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