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Conditions: GI > Autoimmune Hepatitis > Flashcards

Autoimmune Hepatitis Flashcards

1
Q

Pathology of autoimmune hepatitis?

A

Inflammation of the liver due to autoimmune processes

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2
Q

What are the symptoms and autoimmune signs of autoimmune hepatitis?

A

Presents with acute hepatitis

Autoimmune signs

  • Fever
  • Malaise
  • Urticaria
  • Pleurisy
  • Glomerulonephritis

Can be asymptomatic

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3
Q

Aetiology?

A

HLA-DR2

HLA-DR3

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4
Q

Signs?

A

Hepatosplenomegaly

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5
Q

Tests?

A

LFTs

FBC

  • Autoantibodies
  • > ANAs

Liver biopsy
MRCP to rule out PSC

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6
Q

LFT results?

A

Raised ALT and AST

  • ALT > AST
  • Bilirubin raised
  • Albumin down depending on stage
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7
Q

What are ANAs?

A

Anti nuclear antibodies

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8
Q

FBC results?

A

Anaemia from hypersplenism

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9
Q

Treatment of autoimmune hepatitis?

A

IMMUNOSUPPRESSION

  • Steroids
  • Azothiaprine
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Conditions: GI (36 decks)

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