Hepatocellular Cancer Flashcards
1
Q
What does hepatocellular carcinoma happen in the background of?
A
Cirrhosis
2
Q
What liver conditions is hepatocellular carcinoma associated with?
A
Hep B
Hep C
3
Q
Symptoms?
A
Abdominal pain
Weight loss
Anaemia if haemorrhagic tumour
4
Q
Signs?
A
R Hypochondriac mass
Epigastric mass
5
Q
Tests?
A
FBC
LFTs
USS/CT
6
Q
What tumour biomarker should be checked?
A
AFP
7
Q
LFT results?
A
Can be normal
All can be compromised
8
Q
Surgical management?
A
Hepatic resection
Liver transplant
Tumour embolization and ablation
- Alcohol
- Radiofrequency
9
Q
What pharmacological management can be done?
A
Chemotherapy
10
Q
What are the two ways chemotherapy can be administered in hepatocellular carcinoma?
A
Local delivery
- Transcatheter
Systemic delivery
11
Q
Chemotherapy drugs?
A
Sorafenib
Tamoxifen