Hepatocellular Cancer Flashcards

1
Q

What does hepatocellular carcinoma happen in the background of?

A

Cirrhosis

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2
Q

What liver conditions is hepatocellular carcinoma associated with?

A

Hep B

Hep C

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3
Q

Symptoms?

A

Abdominal pain
Weight loss
Anaemia if haemorrhagic tumour

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4
Q

Signs?

A

R Hypochondriac mass

Epigastric mass

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5
Q

Tests?

A

FBC
LFTs
USS/CT

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6
Q

What tumour biomarker should be checked?

A

AFP

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7
Q

LFT results?

A

Can be normal

All can be compromised

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8
Q

Surgical management?

A

Hepatic resection

Liver transplant

Tumour embolization and ablation

  • Alcohol
  • Radiofrequency
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9
Q

What pharmacological management can be done?

A

Chemotherapy

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10
Q

What are the two ways chemotherapy can be administered in hepatocellular carcinoma?

A

Local delivery
- Transcatheter

Systemic delivery

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11
Q

Chemotherapy drugs?

A

Sorafenib

Tamoxifen

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