Plasmodium Flashcards
Member of Class_____
Sporozoa
Causes malaria in ____ and_____
mammals and birds
The asexual cycle (schizogony) takes place in the RBC of_____
vertebrates
The sexual cycle (sporogony) takes place in
mosquitoes
Asexual cycle
Schizogony
Sexual cycle
Sporogony
Five Species of Plasmodia
- Plasmodium vivax
- Plasmodium malariae
- Plasmodium falciparum
- Plasmodium ovale
- Plasmodium knowlesi
Plasmodium vivax
Benign Tertian Malaria
Plasmodium malariae
Quartan Malaria or Malariae malaria
Plasmodium falciparum
Malignant Tertian Malaria
Plasmodium ovale
Benign Tertian Ovale Malaria
Mosquito Vectors FMBaLiMa
Anopheles flavirostris
Anopheles mangyanus
Anopheles balabacensis
Anopheles litoralis
Anopheles maculatus
principal vector which breed in slow-flowing, partly shaded clean mountain streams in the Philippines
Anopheles flavirostris
▪ clean stream breeder
Anopheles mangyanus
▪forest rain pool breeder
Anopheles balabacensis
▪ brackish water
Anopheles litoralis
▪ stream breeder
Anopheles maculatus
ERYTHROCYTIC SCHIZOGONY
P. vivax & P. ovale
- young RBC
ERYTHROCYTIC SCHIZOGONY
P. malariae
- older RBC
ERYTHROCYTIC SCHIZOGONY
P. falciparum
- RBC of all stages
THE MALARIA PARASITE
Three developmental stages seen in blood films:
- Trophozoite
- Schizont
- Gametocyte
Features of Plasmodium
nvcs
vacuole
nucleus/ chromatin dot
cytoplasm
stippling
All stages.
Wide range of stages may be seen on given film.
Stages found in circulating blood
P vivax
All stages.
Wide variety of stages usually not seen.
Relatively few rings, gametocytes generally present.
Stages found in circulating blood
P. malariae
All stages
Stages found in circulating blood
P. ovale
Rings and or gametocytes.
Other stages develop in blood vessels of internal organs but are not seen in peripheral blood except in severe infections.
Stages found in circulating blood
P. falciparum
Size of RBCs
• Enlarged:
Size of RBC
P. vivax
P. ovale
Size of RBCs
Not enlarged:
Size of RBCs
P. falciparum
P. malariae
Infection of RBCs
• Single:
Infection of RBCs
• suggestive
usually of P. vivax
Infection of RBCs
Multiple:
Infection of RBCs
• common to P. falciparum
Presence of stipplings or clefts
P. vivax or P. ovale
• Stipplings clearly visible (Schuffner’s )
Presence of stipplings or clefts
P. falciparum or P. malariae
Stipplings not clearly visible