Physiology of Vessels Flashcards
The regulation of blood pressure must change in response to ______.
cellular activity
a collection of mechanisms that influence the active and changing circulation of blood
hemodynamics
Circulation control mechanisms must accomplish two functions:
- maintain circulation
- vary the volume and distribution of the blood circulated
_____ is the only means by which cells can receive materials necessary for survival and have wastes removed.
circulation
Primary Principle of Circulation: Blood flows because a ________ exists between different parts of its volume; this is based on Newton’s first and second laws of motion.
pressure gradient
the symbol used to represent a pressure gradient. ___ represents the higher pressure and ___ represents the lower pressure.
P1-P2
- P1
- P2
A _____ gradient is needed to maintain blood flow through a local tissue
perfusion pressure (PP) gradient
A blood pressure gradient drives blood flow from the ______ to the _____.
right ventricle to the left atrium
fluid always travels from high pressure to low pressure. This is called
pressure gradient
The primary determinant of arterial blood pressure is the ____ of blood in the arteries
volume
A ____ relationship exists between arterial blood pressure and arterial blood volume
direct
volume of blood pumped out of the heart per unit of time.
cardiac output (CO)
the amount the cardiac output can increase above the resting cardiac output
cardiac reserve
Within limits, the longer or more stretched the heart fibers are at the beginning of contraction, the stronger the contraction.
The amount of blood in the heart at the end of diastole determines the amount of stretch or preload placed on the heart fibers
Starling’s Law of the heart
Frank-Starling mechanism
factors that affect strength of myocardial contraction and therefore stroke volume
inotropic factors
one mechanical factor that helps determine stroke volume:
myocardial fibers at the beginning of ventricular contraction.
Contractility can also be influenced by chemical factors:
- neural: norepinephrine
- endocrine: epinephrine
- triggered by stress, exercise
ratio of stroke volume to end-diastolic volume
ejection fraction
usually expressed as a percentage
In a healthy adult, the ejection fraction is at least __%
55%
the pumping work the heart must do to push blood into the arteries
afterload
the harder it is to push blood out of the ventricles, the lower the _____.
stroke volume.
Abnormally high afterload from flow resistance in the arteries can cause _____.
heart failure
_______ and _______ are located in the aorta and carotid sinus.
They affect the autonomic cardiac control center in the Medulla, and therefore parasympathetic and sympathetic outflow, to aid in control of blood pressure.
Cardiac pressoreflexes:
aortic baroreceptors and carotid baroreceptors
factors that change the rate of the heartbeat
chronotropic factors
_________ reflex:
- located at the beginning of the internal carotid artery
- sensory fibers from carotid sinus baroreceptors run through the carotid sinus nerve and the glossopharyngeal nerve to the cardiac control center
- parasympathetic impulses leave the cardiac control center and travel through the vagus nerve to reach the SA node
carotid sinus reflex
_____ reflex:
- sensory fibers extend from baroreceptors in the wall of the aortic arch through the aortic nerve and through the vagus nerve to terminate in the cardiac control center
- stimulation causes the cardiac control center to increase vagal inhibition, thus slowing the heart
aortic reflex