Nervous System Cells Flashcards
Central Nervous System consists of (2):
- Brain
- Spinal cord
Structural and functional center of the nervous system that integrates sensory information
Central Nervous System
Nerves that lie in “outer regions” of the nervous system
Peripheral Nervous System
nerves that originate from the brain and brain stem (12 pairs)
cranial nerves
nerves that originate from the spinal cord (31 pairs)
spinal nerves
All incoming sensory pathways (northbound)
afferent division
all outgoing motor pathways (southbound)
efferent division
system that carries information to the skeletal muscle (or glands)
somatic motor division
system that carries feedback information from skeletal muscle (or glands) to ____ integration centers in the CNS
somatic sensory division
somatic
carries info to the visceral effectors (smooth and cardiac muscles and glands)
efferent division of autonomic nervous system
carries feedback info to _____ integrating centers in the CNS
afferent/visceral sensory division
autonomic
The autonomic nervous system is normally _____.
involuntary
The somatic motor division is ____ and under conscious control.
voluntary
2 subdivisions of efferent division of ANS:
- sympathetic division
- parasympathetic division
prepares the body for immediate threats to its internal environment (fight, flight, or freeze response)
sympathetic division
coordinates body’s normal resting activities (rest and repair)
parasympathetic division
2 main types of cells in the nervous system:
- neurons
- glial cells (neuroglia)
excitable cells that make nervous system functions possible. Form the “wiring” of the nervous system’s information circuits.
neurons
cells that do not usually conduct information. They support the function of neurons in various ways.
(Helper cells)
glial cells (neuroglia)
5 main types of glial cells:
- astrocytes
- microglia
- ependymal cells
- oligodendrocytes
- schwann cells
star-shaped, largest, and most numerous type of glial cell. They transfer nutrients from blood to the neurons, help recycle neurotransmitters at synapses, and form tight sheaths around brain capillaries
astrocytes
double barrier made up of astrocytes and the endothelial cells that make the capillary walls
blood-brain barrier, BBB
The ________ helps maintain a very stable environment required for normal functioning of the brain by forming a barrier that regulates passage of most ions between the blood and brain tissue.
Blood-Brain Barrier, BBB
Some ions could disrupt the transmission of nerve impulses if _____ did not exist.
Blood-Brain Barrier, BBB
small, usually stationary cells that engulf and destroy microorganisms and cellular debris. The “Macrophages” of the nervous system.
Microglia
____ are usually quiet and inactive, but if brain tissue is inflamed or degenerating, they will enlarge and become mobile, allowing them to carry out phagocytosis.
Microglia
cells that form thin sheets that line fluid-filled cavities in the CNS. Some take part in producing the fluid that fills these spaces. Some have motile cilia that help circulate fluid.
ependymal cells
The fluid filled cavities in the CNS
ventricles
smaller than astrocytes with fewer processes. They hold nerve fibers together and produce the myelin sheath around nerve fibers in CNS only
Oligodendrocytes
cells found only in the PNS. They support nerve fibers and form myelin sheaths.
Schwann cells
gaps in the myelin sheath
Nodes of Ranvier
where the nucleus and cytoplasm are squeezed to perimeter. Essential in normal growth and regeneration.
Neurolemma
special schwann cells that surround the cell body of a neuron, usually in ganglia
satellite cells
excitable cells that initiate and conduct impulses to make all nervous system functions possible
neurons
The 3 components of a neuron:
- cell body
- dendrites
- axon
AKA perikaryon or soma
cell body
- provides neurotransmitters needed for transmission of nerve signals
- provides proteins for maintaining and regenerating nerve fibers
- contains mitochondria, which are transported to end of axon
cell body
cells that do not have a myelin sheath, and conduct nerve signals to the cell body of the neuron
dendrites
Each neuron has one or more _____, which branch from the cell body
dendrites
portion of the cell body from which the axon extends
axon hillock
part of neuron that conducts nerve impulses away from the cell body of the neuron. Is sometimes covered by a myelin sheath
axon
zone where dendrites and cell body receive stimulus and initiates impulse
Input zone
zone where axon hillock collects all the nerve impulses arriving from the cell body and dendrites and decides whether to send the impulse any farther along the neuron
summation zone
zone where the axon conducts the nerve impulse from the axon hillock all the way to the end of the neuron
conduction zone
zone where telodendria and synaptic knobs (release neurotransmitters)
output zone
The 3 structural classifications of neurons:
- multipolar
- bipolar
- unipolar
structural class: one axon and several dendrites
multipolar
structural class: only one axon and one dendrite; least numerous kind of neuron
bipolar
structural class: one process comes off neuron cell body but divides almost immediately into two fibers; central process and peripheral process
(pseudo)unipolar
______ are always sensory
unipolar
a signal conduction route to and from the CNS, with the electrical signal beginning in receptors and ending in effectors
reflex arc
simplest form; consists of an aferrent neuron and an efferent neuron
two-neuron arc
most common; consists of an afferent neuron, an interneuron, and an efferent neuron
three-neuron arc
conduct impulses from afferent neurons to or toward motor neurons. They lie within CNS
Interneurons
____ ____ are an example of regulatory feedback loop
Reflex arcs
The location where nerve signals are transmitted from one neuron to another. Located at junction of synaptic knob of one neuron and dendrites or cell body of another neuron
synapse
bundles of peripheral nerve fibers held together by several layers of connective tissue that form a sheath
nerves
bundles of nerve fibers located within the CNS
tracts
_____ : surrounds Schwann cell
endoneurium
____ : surrounds a fascicle
perineurium
____ : surrounds a whole nerve (and numerous fascicles and the blood vessels that supply them)
epineurium
Most nerves in the nervous system are ____ ____, and contain both afferent and efferent fibers.
mixed nerves
____ do not have connective tissue coverings.
tracts
bundles of myelinated fibers
white matter
made up of cell bodies and unmyelinated fibers
gray matter
Gray matter: In the CNS bundles of cell bodies referred to as ____.
nuclei
gray matter: In the PNS bundles of cell bodies referred to as ____.
ganglia
____ have a limited capacity to repair themselves.
neurons
Nerve fibers can be repaired if the damage is not extensive. The ____ and ____ have to be intact.
cell body, schwann cell
- The distal portion of the axon and the myelin sheath regenerate
- Macrophages remove debris
- Remaining neurolemma and endoneurium form tunnel from the point of injury to the effector
- New schwann cells grow in the tunnel to maintain a path for regrowth of the axon
- cell body reorganizes itself to provide the necessary proteins to extend the remaining healthy portion of the axon
- axon sprouts appear.
- Skeletal muscle cell atrophies until the nervous connection is reestablished
Stages of nerve repair
CNS neurons lack the _____: no tunnel to guide the repair from the point of injury
neurolemma
____ fill the damaged areas and block regrowth within the CNS
astrocytes
Most injuries to the ____ and ___ cause permanent damage.
brain, spinal cord