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Derm 2020 > Physical Agents > Flashcards

Physical Agents Flashcards

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Dermatology Board Prep flashcards
1
Q

Second degree deep burns destroy deep follicular structures

A

True

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2
Q

Frostbite needs rapid rewarming

A

True

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3
Q

Phases of frostbite

A

1 - cooling
2. -thawing and rewarming
3 - extension of injury
4 - resolution

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4
Q

Pernio (chilblains) —> usually women and elderly, children in homes lacking central healing

A

True

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5
Q

Perniosis in children have a longer course

A

False - older individuals, younger pt improve spontaneously

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6
Q

Pernio - erythrocyanotic macules, papules, plaques in which distribution ?

A

Toes, fingers, ears, nose, heels

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7
Q

Histo of perniosis

A

Dermal oedema
Fluffy perivascular oedema
Superficial and deep lymphohistiocytic infiltrate with peri eccrine accentuation
Infiltrate is predominantly T lymphocytes

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8
Q

Associations of perniosis

A

Poor nutrition
Eating disorders
Haem malignancy
Autoimmune systemic disease (LE)

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9
Q

How does actinic prurigo differ from PMLE

A

Typically early age of onset with involvement of the dorsal nose , lips and conjunctivae

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10
Q

PMLE is immediate type hypersensitivity

A

False, delayed type

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11
Q

PMLE is mediated by T helper cells early then T suppressor cells at 72h

A

True

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12
Q

PMLE occurs in as little as 1 minute

A

False 10 min

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13
Q

Priming phenomenon also exists in chronic actinic dermatitis

A

False, PMLE with delay after exposure usually 6hr or more

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14
Q

Action spectrum of PMLE is UVA, UVB and rarely visible light

A

True

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15
Q

DDx PMLE

A 
cutaneous lupus including tumid lupus 
Porphyria (when vesicles involved)
Solar urticaria
Photoexacerbated dermatoses
Photo drug eruption 
Jessner’s lymphocytic infiltrate
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16
Q

Provocation testing not usually possible with PMLE

A

False - can be provoked by irradiating very small areas of skin monochromator

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17
Q

PMLE histo

A

Variable epidermal spongiosis
Superficial and deep perivascular and periappendegeal lymphohistiocytic dermal infiltrate, often with scattered eos and neuts
Significant dermal oedema

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18
Q

Actinic prurigo Perennial itchy papules and vesicles during acute flares

A

True

19
Q

Actinic prurigo most commonly commences in childhood

A

True

20
Q

Gene involved in actinic prurigo

A

HLA DRB1*0407

21
Q

Actinic prurigo action spectrum

A

Usually both UVA and UVB (rarely UVA only)

22
Q

Chronic actinic dermatitis broad spectrum but predominantly UVA

A

False,UVB

23
Q

Chronic actinic dermatitis occurs seasonally

A

True

24
Q

Chronic actinic dermatitis is less common in temperate climates

A

False - more common

25
Q

Pseudolymphomatous changes occur in the setting of chronic actinic dermatitis

A

True

26
Q

Actinic reticulohistiocytoma has pseudolymphomatous and nodular prurigo-like changes

A

True

27
Q

Solar urticaria is induced by UVA, visible light and rarely UVB

A

True

28
Q

10% of CAD resolve spontaneously in 6-7years

A

False 1-2 years

29
Q

Solar urticaria usually exhibits hardening

A

False -= does not typically

30
Q

Monochromator testing is particularly useful in solar urticaria

A

True as get urticarial reaction

31
Q

Hydroa vacciniforme more common in males

A

True

32
Q

Areas most commonly affected by hydroa vacciniforme

A

Cheeks, nose, ears, back of hands most commonly affected

33
Q

Hydroa vacciniforme scars painlessly

A

False- painful

34
Q

UVA wavelengths are implicated in hydroa vacciniforme

A

True

35
Q

Need to assess immediate and delayed response with monochromator testing

A

True

36
Q

Hydroa vacciniforme DDx

A

Hart up disease, EPP, Bullous LE, CTCL (HV-like CTCL reported in children)

37
Q

Hydroa vacciniforme natural course

A

Usually improves and resolves by later teen years , spontaneous resolution in 60%, mean duration of 9 years

38
Q

Hardening does not help hydroa vacciniforme

A

False - can do NBUVB in springtime

39
Q

Complications of hydroa vacciniforme

A

Scarring, ocular complications, cartilage destruction

40
Q

Hydroa vacciniforme aetiology unknown but relates to which virus?

A

EBV - virus can be found in inflammatory infiltrate in pt with HV in Asia.

41
Q

HV like presentation of T cell lymphoma has been reported in children

A

True

42
Q

Drugs causing photo onycholysis

A

Psoralens
Tetracyclines
PDT
Ciprofloxacin

43
Q

What are the types of xanthomas

A

TV TED (PXP)

Tendinous
Tuberous 
Eruptive
Dyslipidaemic (includes plane, palmar and xanthelasma)
Verruciform xanthoma
44
Q

Eruptive xanthoma seen in setting of primary or secondary hypertriglyceridaemia

A

True

Derm 2020 (59 decks)

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