Emergency Derm Flashcards
Anaphylaxis - hypotension and broncos pass, even if typical skin features are not present
True
For pregnant women 0.3mg if adrenaline should be used
True
3-20% have biphasic reaction of anaphylaxis
True
What testing can be performed for type 1 hypersensitivity
RAST IgE
Skin prick test (Anaphylaxis is a relative contraindication. Absolute CI’s include diffuse derm condition present, severe dermographism, poor pt co-operation, pt unable to stop drugs interfering with test)
Provocation test
Exposure test
Neisseria meningitidis is transported by droplets from infected patients but not healthy carriers
False - can be transmitted from healthy carriers
Early petechiae lesions from meningococcal disease are caused by organisms in capillary endothelium + DIC with necrosis of the vessel wall or thrombosis
True
N. Meningitidis group B is more common in tropical regions
False. Gp A tropical, Gp B in Europe
Toxic shock syndrome can occur in patients with infections associated with burns, insulin pump infusion sites, post partum infection
True
The toxin associated with TSS is TSST-3
False - TSST-1
Neonatal toxic shock due to TSST-1 producing S. aureus is usually fatal
False - usually mild due to immature relatively anergy state of T cells in newborn
TSS is thought to occur via superantigen-mediated cytokine storm through a powerful activation of T cells, macrophages - leads to respiratory failure , vascular leakage and shock
True
List complications of toxic shock syndrome
WAGU VCR
Weakness, myalgias, fatigue - prolonged
Amenorrhea
Gangrene
Upper limb paraesthesia
Nail shedding / Beau’s lines
Vocal cord paralysis
Carpal tunnel syndrome
Renal impairment
Staph scalded skin syndrome is Nikolsky negative
False - positive
Strep toxic shock syndrome is less fatal with localised skin involvement
False more fatal, but less common to have erythroderma
In staph scalded skin syndrome, blood cultures can be positive in adults
True , but negative in children
