Photodermatology

Question 1

What are treatments of cutaneous photosensitivity

Answer 1

avoidance, clothing, suncream, PUVA,

Question 2

What is a porphoryia

Answer 2

a deficiency of the enzymes that break down porphyrins which leads to accumulation of porphyrins

Question 3

Name two main common skin porphyrias

Answer 3

acute phototoxicity and blistering and fragility

Question 4

Name the commonest type of porphyria that presents as skin manifestations

Answer 4

Porphyria cutanea tarda

Question 5

Name some typical presentatoins of PCT

Answer 5

Blistering, fragility, hyperpigmentation, solar urticaria, hypertrichosis

Question 6

What causes PCT?

Answer 6

Alcohol, viral hepatitis, oestrogens and haemochromatosis

Question 7

What is erythropoietic protoporphyria

Answer 7

A deficiency in ferrocheltase causes a build up of protoporphyrins.

Question 8

How does Erythropoietic protoporphyria present?

Answer 8

Burning/ itch skin, usually during childhood

Question 9

Is erythropoietic porphyria genetic or not?

Answer 9

Genetic

Question 10

How do you manage EPP

Answer 10

6 monthly LFTs and RBC porphyrins. Prophylactic phototherapy, antioxidants.