Photocarcinogenesis Flashcards

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1
Q

What is carcinogenesis

A

process by which a normal cell because a malignant cancer cell

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2
Q

What are oncogenes

A

gain of function

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3
Q

What are tumour suppressors

A

loss of function

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4
Q

What factors can cause carcinogenesis

A

DNA damage, UV exposure, inherited defects

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5
Q

Is UVA direct or indirect DNA damage

A

Indirect- penetrates more deeply into skin

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6
Q

UVB is less harmful true or false

A

False- x1000 more damaging

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7
Q

What happens in UV induced immunosuppression

A

dendrites lose ability to present antigens

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8
Q

What virus is a factor of skin cancer

A

HPV

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9
Q

Name some phytotoxic drugs

A

NSAIDS, voriconazole (antifungal), Thiazide diuretics, azathioprine

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10
Q

What is treatment choices for premalignancy

A

Cryotherapy, surgery, topical agenices, photodynamic therapy

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