Dermatitis and Eczema Flashcards
What does hyperkeratosis mean
increase thickness of keratin layer
What does parakeratosis mean?
persistence of nuclei in keratin layer
Acanthosis
Increased thickness of epidermis
What is papillomatosis
Irregular epithelial thickening
Spongiosis
oedema between keratinocytes
Does dermatitis= Eczema?
YES
What histology is dermatitis generally
spongiotic deramtitis
Name an example of contact allergic dermatitis
Nickel allergy, latex
What is the immunopathology of contact allergic dermatitis
Langerhans cells are antigen presenting cells which present to Th cells in dermis. They migrate to lymphatics and then when reexposed to antigen, inflammatory infiltrate is present
How can contact allergy dermatitis be identified?
Patch testing
What is the difference between allergy and irritant
irritant is non specific irritation such as soap, detergent, water and oil
irritant dermatitis is usually found in flexures true or false
false
How would you describe pruritus using 2 mechanisms
Itch> scratch ect ect
What would atopic eczema present as
severe itch, ill defined erythema, scaling, flexural distribution.
What else is atopic eczema associated with
hayfever, allergic rhinitis, asthma, food allergy
