Pigmented lesions Flashcards

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1
Q

What hair colour does Phaeomelanin cause

A

red

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2
Q

What are actinic lentigines

A

age or liver spots

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3
Q

how are usual acquired nave formed

A

breakdown of melanocytes: keratinocyte ratio at a number of sites

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4
Q

how many nave does the average human have

A

20-30

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5
Q

What is junctional naevus

A

melanocytes cluster at DEJ

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6
Q

What is compound naevus

A

junctional and in dermis layer of melanocytes

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7
Q

What is intradermal naevus

A

no junctional activity, jus tin dermis

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8
Q

There is no familial risk of dysplastic naevi-> melanoma

A

False, there is up to a 100% chance

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9
Q

Is the epidermis affected in the dysplastic naevi

A

No

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10
Q

What is the Spitz nave

A

Benign, spindle/ epithelioid cell s. Mostly occurs in those under 20

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11
Q

What is the most common cause of malignant melanoma

A

sun exposure/ sunburnt as a child

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12
Q

What are signs of melanoma

A

bleeding, change in mole, change in colour, shape, ulceration

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13
Q

What is the commonest type of malignant melanoma

A

superficial spreading

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14
Q

what does VGP stand for

A

vertical growth phase

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15
Q

can VGP metastasis

A

YES

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16
Q

can RGP metastasis

A

No

17
Q

melanoma

A

100%

18
Q

melanoma >4mm has survival of

A

20%

19
Q

what does the suffix b stand for

A

ulceration- a key factor in diagnosis

20
Q

What is the treatment for melanoma

A

eliptical excision. Some may have a sentinel biopsy. If this is positive, lymphadenectomy. In advanced disease, chemo, radio, immunosup

21
Q

what can ckit mutation melanomas be treated with

A

imatinib

22
Q

where would you normally find a superficial spreading melanoma

A

trunk or legs

23
Q

Is nodular melanoma thought to be the worst of them all?

A

Yup

24
Q

Where does acral lentiginous melanoma affect

A

soles, nails or palms

25
Q

what are seborrheic keratoses

A

warty, stuck on appearance, older people

26
Q

how do you deal with SK

A

reassure, freeze, currette or shave off

27
Q

How to treat melanoma

A

excision, Sentinel biopsy