Immunology

Question 1

Name features of the innate immunity

Answer 1

Non- specific, no memory, first line, invertebrates

Question 2

Name features of an adaptive immunity

Answer 2

Vertebrates, memory, highly specific, tolerance and self limiting

Question 3

How is the keratin layer formed?

Answer 3

By the differentiation of keratinocytes to corneocytes. Important structures are filaggrin and keratin

Question 4

What are the langerhans cells characterised by?

Answer 4

Birbeck granules

Question 5

Where are CD8+ cells found?

Answer 5

Epidermis

Question 6

True or false, both CD4 and CD8 are found in the epidermis

Answer 6

false

Question 7

CD4 Th cells are associated with

Answer 7

Th1- psoriasis, Th2- atopic dermatits and Th17- psoriasis and atopic dermatits

Question 8

What response is associated with mast cells?

Answer 8

IgE

Question 9

where are Class 2 MHC cells found

Answer 9

On APC (B Cells and macrophages) . Present to Th cells

Question 10

In What gene does atopic eczema have

Answer 10

Filaggrin

Question 11

Name secondary immunodeficiency diseases

Answer 11

• AIDS, aging, malignancy, diabetes, burns, alcoholic cirrhosis

Question 12

which 2 antibodies are produced in a type 2 hypersensitivity reaction

Answer 12

IgG and IgM

Question 13

What diseases are affected by type 2 hypersensitivity

Answer 13

HAEMOLYTIC DISEASE OF NEWBORN AND BLOOD TRANSFUSIONS