Pharmacotherapeutics Flashcards

1
Q

what position should a child be in when administering medications

A

standing or at least propped up to 45 degrees

prevents choking/gagging

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2
Q

what is the best way to restrain a child to give medication

A

on parent/guardian lap, facing provider. Parent puts one arm around child’s torso and arms. The other holds the child’s head back by putting a hand on the forehead.

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3
Q

what is the difference between the FDA guidelines and the american academy of peds guidelines when it comes to OTC old medications

A

AAP - discourages use under the age of 6
FDA - discourages use under age of 2

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4
Q

what severe and life threatening side effects can potentially result from the use of OTC cold meds in children

A

Tachycardia, convulsions, and decreased levels of consciousness

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5
Q

why is there increased potential for enhanced toxicity of meds in young children

A

due to metabolism, drug clearance, and drug effects varying according to age

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6
Q

what is the pediatric cough and cold safety surveillance system

A

a system that gains information from the following sources about pediatric cough and cold safety

  • The National Poison Data System of the American Association of Poison Control Centers
  • The FDA Adverse Event Reporting System (FAERS)
  • US-based news/media reports
  • English-language medical literature
  • Manufacturer postmarketing safety databases
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7
Q

where can you find the correct dosing for OTC mediactions in peds

A

the medicine’s “drug facts” label.

read carefully and follow directions!

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8
Q

what is the standard dosing method recommended by the AAP

A

a syringe in milliliters instead of a teaspoon

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9
Q

do not give a child 2 medications that have the same ____________ becuase it could be fatal

A

active ingredient

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10
Q

what is avoided in children under 18 due to the possibility of developing reyes syndrome

A

aspirin or aspirin containing products

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11
Q

For Sudafed, what is the:
active ingredient
MOA
main use
side effects

A
  • active ingredient: pseudoephedrine
  • MOA: sympathomimetic that causes vasoconstriction by stimulation of alpha receptors in mucosa
  • main use: decongestant
  • side effects: dizziness, difficulty sleeping, nervousness, tachycardia, HTN, irritability
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12
Q

what is the alternatives to sudafed

A

topical decongestants such as phenylephrine/oxymetazoline (afrin)

Less systemic effects, however could cause rebound congestion

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13
Q

For Robitussin/Delsym what is the:
Active ingredient:
MOA:
Side effects:

A
  • Active ingredient: dextromethorphan (isomer of codeine)
  • MOA: acts on cough center of medulla to suppress cough
  • Side effects: nausea, sedation, dizziness, abdominal pain
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14
Q

what patients should avoid taking Delsym

A
  • asthma
  • CF
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15
Q

for mucinex what is the:
Active ingredient:
MOA:
Side effects:

A
  • Active ingredient: Guaifenesin
  • MOA: increases resp tract fluid secretions and loosens bronchial secretions by reducing viscosity (aids in the clearance of mucous)
  • Nonproductive cough becomes more productive, less frequent, less irritating
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16
Q

what are other remedies for coughs/cold

A
  • honey over age 1 - helps w cough
  • nasal saline - keeps nasal passages moist and helps avoid stuffiness
  • bulb suction of mucous
  • elevate head of bed
  • cool mist vaporizer/humidifier
  • antihistamines
  • tylenol/motrin/ibuprofin for fever
  • hydration
17
Q

how often can tylenol be dosed

A

Q4 hours

18
Q

How often can motrin/ibuprofin be dosed

A

Q6-8 hours for aches, pains, or fever.

patient MUST be older than 6 months.

19
Q

what is pediatric dosing measured by

A

weight and age

20
Q

what is the difference in the developmental pharmacokinetics in pediatric vs adult population?

A
  • ↓GI but ↑IM absorption
  • ↑body H2O but ↓lipids
  • Limited protein binding
  • ↑liver/body wt ratio
  • Immature enzymes
  • ↑brain/body wt ratio; ↑blood brain barrier permeability
  • Immature renal function
21
Q

what are the 6 steps of pediatric dosing

A
  1. find medication dosing amount along w mg/ml amount
  2. convert pt weight to kg (lbs/2.2)
  3. multiply dose amount by kg
  4. divide by how many times the pt takes the meds per day
  5. convert to mL by dividing mg dose by the amount of medication in each 5mL of medication
  6. dispense amount