Cong infections trigger Flashcards

1
Q

protozoan

A

toxoplasmosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

screen moms with cervical LAD and high fever.

what would the screening show?

A

toxoplasmosis

US showing clacifications or cerebral ventricular dilation are MC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cat feces and raw meat

A

toxoplasmosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

s/s include hydrocephalus, microcephaly, anemia, and chorioretinitis

A

toxoplasmosis:

Cataracts/chorioretinitis
Calcifications in brain
Hearing loss
Hydrocephalus
Anemia
Seizures
Microcephaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

s/s shows seizures, hearing loss, cataracts and calcifications of the brain

A

toxoplasmosis

Cataracts/chorioretinitis
Calcifications in brain
Hearing loss
Hydrocephalus
Anemia
Seizures
Microcephaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

focal necrotizing retinitis

A

toxoplasmosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

dx with ELISA and CXR that shows diffuse cortical calcifications

A

toxoplasmosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

tx with spiramycin if <14 weeks gestation.

what about after 14 weeks?

A

toxoplasmosis

> 14wks gestation = pyrimethamine + Sulfadiazine + folic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

eye exam every 3 months for 18 months + pharmacological tx

A

toxoplamosis postnatal tx.

also Pyrimethamine + sulfadiazine + folinic acid for 1 yr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

PDA and pulm artery stenosis, hearing loss, mental retardation, microcephaly and cataracts

what symptom are we missing?

A

rubella

blueberry muffin syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

low platelet count (thrombocytopenia)

A

rubella (petechiae and purpura)

can also be seen in CMV!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

infants with this disease are chronically infected for a whole year and shed the virus into their stool, urine and respiratory secretions

A

rubella

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Doublestranded DNA Herpes Virus

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

transmissible through saliva, blood and breastmilk

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

MC congenital infection

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

leading cause of NON hereditary sensorineural hearing loss

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

elevates LFTs, thrombocytopenia, elevated bilirubin

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

dx with urine/saliva test and a CT scan which will show periventricular lesions

A

CMV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

not treated unless there is SEVERE sickness and you recieve approval from the FDA

A

CMV

ganciclovir and valganciclovir.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

in a baby who is septic with fever and irritability but a negative bacteriologic culture, what should we suspect?

A

disseminated HSV infection

will have abnormal CSF and possible liver dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

scarring eye damage, skin lesions, ulcerations

A

HSV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

dx made w specimin cultures of anything that touched amniotic fluid. could also do a PCR of blood/urine/CSF

A

HSV

23
Q

IV Acyclovir (60mg/kg/d) for 2-3 weeks

Give to any infant that is suspected to have this

A

HSV

(IV acyclovir is also used in the treatment of active VZV in a baby)

24
Q

cicatrical skin lesions and limb atrophy with cataracts and retinitis.

A

VZV infection

25
Q

can be dx clinically or with a PCR

A

VZV (PCR is of the vesicle base)

26
Q

when is VariZIG used?

A
  • PROPHYLAXIS ONLY
  • preterm of <28 weeks always
  • preterm >28 wks if exposed if mom isnt immunized
  • exposed to mom who has it 5days prior to 2 days after birth.

(this is up to date because i could not understand the slides oml)

27
Q

s/s include arthropathy, fetal anemia, myocarditis and a rash

A

parvo B19 (rash = slapped cheeks)

28
Q

dx is serologic IgG and IgM testing via umbilical cord blood sample.

A

Parvo B19

29
Q

once this infection is found, mother must recieve US weekly to assess for signs of hydrops fetalis

A

Parvo B19

30
Q

transplacental transmission is seen in which diseases?

A
  • HSV
  • Syphilis
  • HIV
  • parvo
  • zika
  • maybe CMV? pic below idk
31
Q

this presents asymptomatic at birth

A

syphillis

32
Q

generalized LAD, skeletal abnormalities, rash, white/bloody nasal discharge, hepatomegaly

A

syphilis presentation prior to 2 years

33
Q

hutchinsons triad, what is it and when do we see it

A
  • interstitial keratitis, 8th cranial nerve deafness, and hutchinsons teeth
  • seen in syphilis after 2years
34
Q

rhagades, bowing shins, mulberry molars, saddle nose and clutton joints

A

syphilis after 2 years of age (late s/s)

35
Q

Direct visualization via dark field exam of bodily fluids is the diagnostic for what

A

syphilis

36
Q

tx w PCN G

A

syphilis

37
Q

presents w bilateral conjunctivitis and PNA

A

chlamydia

38
Q

Suspected in any infant under 1 month with conjunctivitis

A

chalymidia

39
Q

culture of conjunctival and NP is dx for what

A

chlamydia

40
Q

oral erythromycin

A

active chlamydial infection

41
Q

bilateral purulent conjunctivitis w profuse exudate

A

gonorrhea

42
Q

erythromycin ointment

A

prophylactic tx for chlamydia and gonorrhea

43
Q

gram stain of conjunctival exudate

A

gonorrhea

44
Q

tx w rocephin

A

gonorrhea

45
Q

zidovudine for 6 weeks

A

HIV antiviral prophylaxic

46
Q

Interferon and ribavirin as tx

A

congenital hep C

47
Q

Hoarseness (airway)

A

congenital HPV

48
Q

Arthropod flavivirus from mosquitoes, with placental transmission

A

zika

49
Q

diagnosed with a blood test at 18months of age and confirmed with genotyping

A

Hep C

Anti-HCV (HCV antibody testing) present in blood after 18 months of age is indicator; confirmed with HCV RNA test, then HCV Genotyping

(test after 18 mo or else may fasle positive due to mom having antibodies)

50
Q

s/s include ocular scarring, ventriculomegaly, microcephaly and arthrogryposis

A

zika

51
Q

severe microcephaly with skull collapse, subcortical cacifictations and craniofacial disproportion

A

zika

52
Q

serum + urine for RNA via PCR is a definitive diagnosis infection in these patients

A

zika

just look over this plz

53
Q

primary SCREENING tool is a head US

A

zika