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Pharmacological Profile Flashcards

1
Q

what are classes of psychotherapeutic

A

Sedatives and Hypnotics

Antianxiety Drugs

Antidepressants

Antipsychotic

CNS Stimulants

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2
Q

what class of drug cause a dose-dependent depression of the Central Nervous System

A

Sedatives and Hypnotics

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3
Q

what drug class depress the sensory cortex, decrease motor activity, alter cerebellar function, and produce drowsiness, sedation, and hypnosis. In

A

Sedatives and Hypnotics

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4
Q

what drug classification is contraindicated with a a Hypersensitivity to phenobarbital, barbiturates or any component of the formulation;

A

Sedatives and Hypnotics

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5
Q

antianxiety drugs can be subdivided into

A

Benzodiazepines

Non- Benzodiazepines

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6
Q

Benzodiazapine Bind to what specific benzodiazepine receptors which enhances the binding of this inhibitory neurotransmitter.

A

GABA receptor complex,

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7
Q

do Benzodiazepine have analgesic properties.

A

No

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8
Q

non benzodiazepines antianxiety act on what

A

the brain’s dopamine and serotonin receptors.

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9
Q

what are counterindications of antianxiety medicaations

A

Do not use with patients who are

comatose

have pre- existing CNS depression.

uncontrolled severe pain

pregnancy or lactation

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10
Q

what are examples of Benzodiazepines

A

Alprazolam: Xanax

Diazepam: Valium

Lorazepam: Ativan

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11
Q

what are examples of Non- Benzo

A

Buspirone hydrochloride: Bu Spar

Hydroxyzine: Atarax

Sertraline (SSRI): May be used long term.

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12
Q

what are the classes of antidepressants

A

Tricyclic antidepressants (TCAs)

Monoamine Oxidase Inhibitors (MAOI)

Selective Serotonin Reuptake Inhibitors (SSRI)

Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Serotonin Reuptake inhibitor/Antagonist

Dopamine/Norepinephrine-Reuptake Inhibitor

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13
Q 
what antidepressant class works by Increase levels of norepinephrine and serotonin by inhibiting their
reuptake and blocking the action of acetylcholine.
A

Tricyclic antidepressants TCA

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14
Q

what antidepressant class works by Inhibits the activity of Monoamine oxidase resulting in increased endogenous neuro-hormones.

A

MAOI

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15
Q

what antidepressant class works to Increasing serotonin by inhibiting neuronal uptake to CNS.

A

Serotonin-norepinephrine reuptake inhibitors SSRI

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16
Q

antidepressant drugs can be used for

A

Depressive symptoms,
Anxiety
Obsessive Compulsion Disorder,
Smoking cessation: (Bupriopion-wellbutrin

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17
Q

delete

A

delete

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18
Q

delete

A

delete

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19
Q

delete

A

delete

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20
Q

TCA should be administered within how many days of MAOI

A

14 days

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21
Q

delete

A

delete

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22
Q

how long do antidepressants take to work

A

4-6 weeks

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23
Q

antidepressants should not be taken with what plant

A

St. johns wort

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24
Q

what medication Block dopamine receptors in the brain; also alter dopamine release and turnover.

A

Antipsychotic

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25
antipsychotics are broken into what classifications
“typical” (1st Generation) “atypical” (2nd Generation)
26
what classification of antipsychotics have fewer side effects
“atypical” (2nd Generation)
27
Amphetamines and Anorexiants fall in what drug classification
CNS Stimulants
28
what drug classification Produce CNS stimulation by increasing levels of neurotransmitters in the CNS.
CNS Stimulants
29
what drug classification Reduction of excitability of the neurons of the brain
Anticonvulsants
30
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31
what drug classification act on the chemoreceptor trigger zone to inhibit nausea and vomiting by depressing the sensitivity of the vestibular apparatus of the inner ear.
Anti-emetic
32
Anti-emetic are used for what
Antiemetic: Prophylaxis or treatment of nausea or vomiting. Antivertigo: Treatment of vertigo
33
what drug classification inhibiting transport of ions | across neuronal membranes, thereby preventing initiation and conduction of normal nerve impulses.
Anesthetic
34
what antagonist medication dissociates the pt from surroundings
ketamine
35
ketamine usually increases what vitals
BP HR Cardiac output (CO)
36
how does ketamine produce analgesia
excites opioid receptors within the insular cortex, putamen, and thalamus
37
IM ketamine take anesthetic effect within how many minutes
3 to 4 minutes
38
Local anesthetics are utilized when
prior to minor painful procedures Induction of General or Regional Anesthetic
39
what are adverse reactions of ketamine
increase HR and BP Prolonged emergence from anesthesia increases the risk of laryngospasm
40
what is the dose of ketamine for: IM pain control Analgesia Induction
20-40 mg IM. 10-20mg IV 1-2 mg/kg IV
41
what is the intravenous (IV) induction drug of choice
Propofol
42
what are the four types of analgesics
Salicylate Non-salicylate Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Urinary Analgesics
43
``` what drug class Inhibition of prostaglandins, dilates peripheral blood vessels (cools body), prolong bleeding by inhibiting aggregation of platelets ```
Salicylates
44
an example of Salicylates medication is
aspirin
45
Analgesic and antipyretic is what type of drug class
Non-Salicylate
46
what are example non salicylate medication
Acetaminophen Benzocaine-Menthol
47
what drug classification works to Inhibit the action of the enzyme cyclooxygenase (COX-1 & COX-2 (Nonselective) or Cox 2 -Selective) which is responsible for prostaglandin synthesis
Nonsteroidal Anti-inflammatory Drugs (NSAIDS)
48
what are examples of NSAIDS:
``` Ibuprofen Indomethacin Ketorolac: Naproxen: Celecoxib Meloxicam ```
49
``` what medication class is a topical bladder and urethral anesthetic and analgesic through an unknown mechanism. ```
Urinary Anesthetic/Analgesic
50
what is a urinary anesthetic analgesic medication
Phenazopyridine
51
what class drug class bind to opiate receptors in the CNS, where they act as agonists of endogenously occurring opioid peptides (endorphins). The result is alteration to the perception of and response to pain and is used for the management be to moderate to sever pain
Narcotic Analgesics
52
what are examples of Narcotic Analgesics medication s
``` Partial Agonist Codeine Fentanyl Hydromorphone Methadone Morphine sulfate Oxycodone Hydrocodone ```
53
what classification of drug is a an opioid antagonist is a receptor antagonist that acts on opioid receptors. and is used for narcotic overdose
Narcotic Antagonist
54
what is a medication example of Narcotic Antagonist dug
Naloxone
55
what class of drug is used to treat allergic reactions
H1 antihistamines
56
what class of drug is used to treat gastric acid conditions
H2 antihistamines
57
what are examples of 1st generation antihistamines
Diphenhydramine: Hydroxyzine Promethazine:
58
what are examples of 2nd generation antihistamines
Cetirizine HCL Fexofenadine Loratadine
59
what medication class is used to treat Common cold, hay fever or upper respiratory allergies, sinus congestion, and pressure. by reducing swelling of nasal passages and enhancing drainage of sinuses
Decongestant
60
what are examples of decongestants
Oxymetazoline HCL: Pseudoephedrine Phenylephrine
61
what class of drug Release stimulants and reuptake inhibitors that increase the levels of endogenous catecholamine’s. and is used to Reversible Airway Obstruction caused by bronchospasm due to bronchial asthma, exercise-induced bronchospasm, bronchitis, emphysema, and other Obstructive pulmonary disease
Beta² Agonists
62
what are Beta² Agonists drugs used for
Reversible Airway Obstruction caused by bronchospasm due to bronchial asthma, exercise-induced bronchospasm, bronchitis, emphysema, and other Obstructive pulmonary disease.
63
what are examples of Beta² Agonists drugs
Albuterol sulfate: | Levalbuterol HCL:
64
what drug classification Antagonizes acetylcholine receptors, producing bronchodilation
Muscarinic Antagonists
65
what class of drugs is used for Symptomatic relief or prevention of bronchial asthma and the management of chronic obstructive pulmonary disease (COPD).
Muscarinic Antagonists used for
66
what class of drug works on Antagonizes acetylcholine receptors, producing bronchodilation.
Muscarinic Antagonists
67
what Muscarinic Antagonists drugs
Ipratropium Tiotropium:
68
what are Broncho constrictive substance released by the body during inflammation.
Leukotriene
69
what class of drug is used to Inhibit the release of substances that cause bronchoconstriction and inflammation from the mast cells in the respiratory tract
Mast Cell Stabilizer:
70
what are examples of mast cell stabilizer
Cromolyn
71
what are examples of Leukotriene Receptor Antagonist:
Montelukast
72
``` what class of drug Produce profound and varied metabolic effects, in addition to modifying the normal immune response and suppressing inflammation ``` Decrease inflammatory process in the airway through inhibiting multiple different inflammatory cytokines.
Inhaled Corticosteroids
73
``` what class of drug is used in the chronic management of reversible airway disease (asthma); intranasal and ophthalmic corticosteroids are used in the management of chronic allergic and inflammatory conditions. ```
Inhalant corticosteroids
74
Normal BP is what range
less than 120/80
75
elevated blood pressure range is
120-129/80
76
elevated blood pressure stage 1 range is
130-139 / 80-89
77
elevated blood pressure stage 1 range is
greater than 140/90
78
what are the steps care regiment 1
life style change
79
what are the steps care regiment 2
the Use of 1 medication | Thiazide Diuretic, ACE-I, ARB, or CCB
80
what are the steps care regiment 3
Increase dose of drugs or combine two drugs.
81
what are the steps care regiment 4
Combine 2-3 of Step 3
82
Consider using ARB instead of an ACE-I in what demographic, why
African American increased risk of angioedema
83
``` what class of drug Lower blood pressure by dilating or increasing the size of the arterial blood vessels. ```
(Angiotensin-converting Enzyme) ACE Inhibitors ARBs
84
what are examples of ACE-Inhibitors and ARB
ACE-I End in "PRI" Lisinopril Captopril Enalapril Ramipril ARB End in "rtan" Losartan Telmisartan

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