Pharmacological Management of Respiratory Infections

Question 1

_____ is the DOC for GAS pharyngitis

Answer 1

penicillin V

Question 2

what would you give to treat GAS in a patient who is allergic to penicillin?

Answer 2

• macrolides

Question 3

which generation of cephalosporin is given to treat GAS?

Answer 3

1st or 2nd

1st: cefazolin, cephalexin
2nd: Cefalcor, cefoxitin, cefotetan, cefamandole

Question 4

what is the DOC for bacterial sinusitis?

Answer 4

amoxicillin

Question 5

which generation of cephalosporin is used as an alternative agent to treat bacterial sinusitis?

Answer 5

2nd: Cefalcor, cefoxitin, cefotetan, cefamandole
3rd: ceftriaxone, cefoperazone, cefotaxime, cefixime

Question 6

a person with bacterial sinusitis is allergic to penicillin. What would you prescribe?

Answer 6

• DOC is amoxicillin

- give macrolides

Question 7

DOC for bacterial otitis media

Answer 7

amoxicillin

Question 8

in choosing the empiric treatment for CAP, what must look for?

Answer 8

• is there comorbidities or immunosuppressing conditions or use of immunosuppressants?
• do the have any use of antimicrobials in the last 3 months

Question 9

what is the DOC for outpatient CAP in a perviously healthy patient without any use of antimicrobials in the past 3 months

Answer 9

• macrolides or doxycycline

Question 10

what is the DOC for outpatient CAP in a patient who is immunosuppressed or has taken antimicrobials in the last 3 months

Answer 10

• respiratory fluoroquinolone OR β lactam + macrolide

this the same treatment regimen for non ICU inpatient CAP

Question 11

treatment method for inpatient CAP in the ICU

Answer 11

• β lactam + azithromycin/respiratory fluoroquinolone

- for penicillin allergic agents give respiratory fluoroquinolone + aztreonam

Question 12

what do you give to penicillin allergic patients with severe CAP inpatient and in the ICU?

Answer 12

• respiratory fluoroquinolone + aztreonam

Question 13

what is the DOC for aspiration pneumonia? 2nd line?

Answer 13

• clindamycin (anaerobes)

2nd line: metronidazole

Question 14

what do you give to treat bordatella pertussis

Answer 14

• macrolide

Question 15

DOC for chlamydia pneumoniae

Answer 15

macrolide, doxycline

2nd line: 3rd or 4th generation fluoroquinolone

Question 16

DOC for non β lactamase producing H. influenza

Answer 16

amoxicillin

2nd line: 2nd or 3rd generation cephalosporin, co-trimoxazole

Question 17

DOC for β lactamase producing H. inlfluenza

Answer 17

2nd or 3rd generation cephalosporin, amoxicillin clavulanic acid