Pharmacokinetics Flashcards
1
Q
What are the two types of metabolism of a drug?
A
(Phase 1) Oxidation; makes the drug more soluble.
(Phase 2) Conjugation; adds a water soluble bit onto a drug to improve overall solubility
2
Q
What is the pharmacology definition of excretion?
A
Vol of plasma cleared of a drug per unit time (rate)
3
Q
What is the definition of bioavailability of a drug?
A
Fraction of unchanged drug reaching the systemic circulation
4
Q
What is the bioavailability of a drug administered by IV?
A
100% as there is no influence on it reaching the systemic circulation.
