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Test 7 > Pharm 9 Headache > Flashcards

Pharm 9 Headache Flashcards

1
Q

Prolongued use of acute Tx

A

Leads to daily headache that doesn’t respond to preventative therapy

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2
Q

NSAIDs

A

For mild episodes without nausea or need for bed rest

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3
Q

Combination analgesics

A

Aspirin, acetaminophen, cafeine

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4
Q

-Metoclopramide-

A

Antiemetic
5HT agonist
D2 antagonist

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5
Q

-Butorphanol-

A

Opioid nasal spray

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6
Q

Opioid + NSAID

A

-Tramadol & Acetaminophen-

Be wary of addiction potential

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7
Q

-Dexamethasone-

A

Corticosteroid

Reduces recurrence, not acute pain

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8
Q

-Reserpine-

A

Triggers migraine

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9
Q

-Sumatriptan-

A

5HT agonist

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10
Q

Ergot alkaloids

A

Fungal derivative
Vasoconstrictors
Nonspecific 5HT & Alpha agonists

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11
Q

Ergot CI

A

Triptans

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12
Q

Ergotamine SE

A

Severe vasoconstriction

Nausea & vomiting

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13
Q

Dihydroergotamine

A

Safer than Ergotamine

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14
Q

-Triptans-

MOA

A

5HT-1 agonists

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15
Q

Triptans with longer half life

A

Naratriptan

Frovatriptan

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16
Q

Triptan Contraindications

A

Preexisting HTN
Ergotamine
MAOI

17
Q

Indication for preventative therapy

A

> 2 bad headaches per month

18
Q

-Valproate-
Indication
MOA

A

Prophylaxis

Anticonvulsant (Enhance GABA)

19
Q

SSRIs

A

Not effective at preventing migrane

20
Q

-Amitriptyline-

A

TCA

Block NE & 5HT reuptake

21
Q

-Nortriptyline-

A

TCA

Block NE & 5HT reuptake

22
Q

-Propranolol & Timolol-

A

B Blockers

Prophylaxis

23
Q

-Verapamil-

A

Calcium Channel Blocker

Low efficacy for migraine, can’t use with BB, Ergot, Triptan

24
Q

-Methylsergide-

A

5HT2 antagonist

High efficacy for migraine Tx

25
Q

-Botox-

A

Inject across head and neck for chronic migraine

26
Q

-Naproxen Sodium-

A

NSAID
Short term prevention
Abort acute migraine

27
Q

-Flurbiprofen-

A

NSAID
Short term prevention
Abort acute migraine

28
Q

Caffeine

A

Increase NE & DA release
Vasoconstriction
Increase NSAID effectiveness

29
Q

-Amitriptyline-

A

NSAID for Tension headache preventative therapy

30
Q

Cluster headache Tx

A

O2 (vasoconstriction)

Intranasal lidocaine

Test 7 (26 decks)

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