Neuro 5B Substance Abuse Flashcards

1
Q

Alcohol MOA

A
  • Facilitate GABA-A

- Inhibit NMDA Glutamate

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2
Q

CAGE parts

A
  • Cut down?
  • Annoyed?
  • Guilt?
  • Eye opener?
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3
Q

Most prominent substance abuse comorbidity

A

Antisocial personality disorder

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4
Q

Chronic effect of alcohol use

A

NTs all do the opposite of the good stuff

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5
Q

Type 1 Alcoholism

A

Men & Women, mild genetic susceptibility, severity determined by stress

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6
Q

Type 2 Alocholism

A

Male-limited
environment has no influence
fathers are criminals

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7
Q

Elevated vital signs during acute intoxication

A

Treat for withdrawal (benzo)

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8
Q

Wernicke’s Encephalopathy

Triad

A

PAG hemorrhages

  • Opthalmoplegia
  • Ataxia
  • Confusion
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9
Q

Barbiturate withdrawal Tx

A

Pentobarbital challenge

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