Neuro G Epilepsy

Question 1

Generalized v Partial seizure

Answer 1

Bilateral v Focal

Question 2

Partial: Complex v Simple seizure

Answer 2

Impairment of consciousness

Question 3

Only seizure with post-ictal period

Answer 3

Tonic-clonic

Question 4

Status epilepticus

Answer 4

Seizures lasting >30min

Question 5

Aura

Answer 5

Partial “warning” seizure

Question 6

Mesial Temporal Sclerosis

Answer 6

Hippocampal gliosis & neuronal loss -> seizures

Question 7

Generalized seizures anatomy

Answer 7

Thalamus -> Cortex

Question 8

Epilepsy Dx

Answer 8

Clinical, not laboratory (EEG not always accurate)

Question 9

Seizure lab finding

Answer 9

Elevated prolactin levels

Question 10

First line Tx:

Partial seizures

Answer 10

Carbamazepine

Question 11

First line Tx:

Generalized seizures

Answer 11

Valproic acid

Question 12

First line Tx:

Absence seizures

Answer 12

Ethosuximide

Question 13

First line Tx:

Status epilepticus

Answer 13

IV Diazepam

IV Phenytoin

Question 14

Metabolism problem

Answer 14

Induce liver enzymes, speed metabolism of oral contraceptives

Question 15

Febrile seizure Tx

Answer 15

none unless significant

Question 16

Absence seizure distinguishing features

Answer 16

No aura or post-ictal confusion

Inherited

Question 17

West Syndrome

Answer 17

Infantile spasms (4-6 months)
-progressive mental retardation

Question 18

Lennox-Gastaut Syndrome

Answer 18

2-10 years

Similar to infantile spasms