Neuro C Multiple Sclerosis

Question 1

Oligoclonal Bands

Answer 1

Show up on autoimmune patients elecrophoresis results

Question 2

MS evoked potential result

Answer 2

Prlolonged evoked potentials (slowed conduction)

Question 3

MS definition

Answer 3

Autoimmune CNS demyelinating disease (patchy), PNS spared

Question 4

MS age of onset

Answer 4

21-40

Question 5

MS geographic incidence

Answer 5

Colder climates have higher risk

Question 6

MS virus etiology

Probable virus

Answer 6

Molecular Mimicry

Canine Distemper Virus

Question 7

MS lesion locations

Answer 7

Periventricular

Question 8

Uthoff’s phenomenon

Answer 8

Symptoms worsen with heat

Question 9

Lhermitte’s sign

Answer 9

Shock from flexing neck forward

Indicates spine lesion, commonly from MS

Question 10

Intranuclear Opthalmoplegia

Answer 10

Frequently due to MLF lesion, one eye stays at midline while other tracks

Question 11

Optic neuritis sign

Answer 11

Marcus-Gunn pupil

-When light is swung to affected eye, dilation is seen (less constriction)

Question 12

Facial Palsy

Answer 12

LMN injury will be entire side of face, UMN injury (MS) will spare forehead

Question 13

Most common MS

Answer 13

Relapsing remitting MS

Question 14

Poser criteria Dx

Answer 14

At least 2 lesions separated by time and space, based on pt history

Question 15

McDonald criteria Dx

Answer 15

MRI, one lesion

Question 16

4 things for every neurological DDx

Answer 16

Syphilis
HIV
Lyme disease
Thyroid disease