Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

random > periodontal pathogens > Flashcards

periodontal pathogens Flashcards

1
Q

says that plaque control is important in periodontal treatment; all plaque bacteria considered bad; any accumulation of micro-organisms at or below the gingival margin causes inflammation

A

non-specific plaque hypothesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

says that specific organisms in dental plaque are the etiological agents; microbial composition of disease sites different from healthy sites

A

specific plaque hypothesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

the specific plaque hypothesis says that ____ and ____ could control local aggressive periodontitis

A

local debridement; systemic antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

gingival health - microflora is predominantly ____ and ____

A

gram positive; facultative anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

in gingivitis- microflora is predominantly _____ and ____

A

gram negative; obligate anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

____, not ____, of the virulent periodontal pathogen are important in disease

A

strains; species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

P. gingivalis with type __ and ___ ____ genotypes = healthy; types ___ and ____ seen in disease

A

type I and V fimA genotypes

types II and IV in disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

pathogen must express ____ and must be in the right location in the site which is :

A

virulence factors; adjacent to epithelium and apical part of pocket

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

____ formation by s. sanguis inhibits A.a

A

peroxide (beneficial species inhibit pathogens)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

____ can increase outer membrane protein expression in P. gingivalis

A

iron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

s. cristatus can inhibit ____ expression of P. gingivalis

A

fimA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

things that affect host susceptibility

A

HIV infection
diabetes
smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

in colonization, ____ on bacteria bind to ____

A

adhesions; host receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

3 examples of host receptors

A

type I or IV collagen
sialic acid
galactosyl residues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

bacteria have ____, outer membrane proteins

A

fimbriae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

4 things that happen during colonization

A

adhesion
coaggregation
nutrient utilization
competitive inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Veillonella uses ____ made by streptococci; campylobacter uses ____ made by selenomonas; porphyromonas uses ____ from blood in sulcus

A

lactate; formate; hemin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

bacteria inhibit each other through competitive inhibition, by producing ____, or in the case of s. sanguis, _____ (to inhibit A.a.

A

bacteriocins; hydrogen peroxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

3 types of host defenses against bacteria

A

desquamation of epithelium
antibodies can prevent binding
phagocytic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

bacteria overcome desquamation of epithelium by:

A

invading epithelium and binding to underlying cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

bacteria overcome antibodies by:

A

IgG and IgA proteases; mimic host antigens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

bacteria overcome phagocytic cells by:

A

leukotoxin; non-lethal suppression of immune cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

world workshop 1996 designated 3 periodontal pathogens:

A

P. gingivalis
A. actinomycetemcomitans
T. forsythia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

red complex bacteria

A

P. gingivalis
T. forsythia
T. denticola

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

characteristics of AA

A

small, non-motile
gram negative
saccharolytic
capnophilic

26
Q

AA is a ____ rod that forms small, convex colonies with a _______ center

A

round-ended; star-shaped

27
Q

high numbers of AA assoc with _____; detected in ____ and in _____

A

localized aggressive periodontitis; active sites; prospective studies

28
Q

host response to AA produces high levels of ____ and ____

A

systemic; local antibody response

29
Q

virulence factors of AA

A 
tissue invasive- epithelial and endothelial cells
leukotoxin
fibroblast inhibiting factor
endotoxin
collagenase
30
Q

AA inhibits growth of ____ and ____ in animal models

A

commensals (strep sanguis); induces disease

31
Q

there are ___ serotypes of AA, based on _____ on surface of organism

A

5; polysaccharides

32
Q

_____ are dominant antigens

A

serotype specific surface antigens (SPA)

33
Q

patients are infected with ___ serotype and serotypes are ____ over time

A

one; stable

34
Q

____ most commonly assoc with LAP in the US; has a role in resistance to ____ and killing by ____

A

serotype b; phagocytosis; PMNs

35
Q

____ is health associated in Finland, disease assoc in Japan

A

serotype a

36
Q

____ and _____ approach is vital to treatment of LAP (by AA)

A

mechanical ; chemotherapeutic

37
Q

____ + _____ effective in reducing bacterial load

A

amoxicillin 500mg ; metronidazole 250 mg

38
Q

____ is required to eliminate tissue reservoirs of AA

A

surgical approach

39
Q

characteristics of P. gingivalis

A

gram negative
non-motile
anaerobic
asaccharolytic rods

40
Q

P. gingivalis is a member of the much investigated ____ group

A

black pigmented bacteroides

41
Q

____ important in protein degradation and in the maturation of _____ such as ____

A

cysteine proteinases (ARG-gingipain and LYS-gingipain); cell surface proteins; fimA fimbrillin

42
Q

Presence of Pg indicates increased risk for ____

A

attachment loss

43
Q

virulence factors of P. gingivalis are involved in:

A
  • colonization and attachment
  • evading (modulating) host responses
  • multiplying
  • damaging host tissues and spreading
44
Q

characteristics of T. forsythia

A

gram negative
anaerobic
spindle-shaped
highly pleomorphic rod

45
Q

T. forsythia requires _____ and co-cultivates with _____

A

N-acetylmuramic acid (NAM); F. nucleatum

46
Q

T. forsythia has a serrated S-layer on cell surface that mediates ____ and _____; it is composed of ____

A

hemagglutination ; adhesion/invasion of epithelial cells; two glycoproteins

47
Q

characteristics of treponema denticola

A
  • species of spirochete
  • gram-negative
  • anaerobic
  • highly motile microorganism
48
Q

T. denticola first identified in _____

A

ANUG (acute necrotizing ulcerative gingivitis)

49
Q

characteristics of prevotella intermedia/nigrescens

A
  • gram negative

- short, round-ended anaerobic rod

50
Q

P. intermedia is the ______ to receive considerable interest

A

second black-pigmented bacteroides

51
Q

p. intermedia has luxuriant growth in _____ and is assoc with ______ gingivitis

A

naphthoquinone; puberty/pregnancy

52
Q

P. intermedia elevated in _____

A

acute necrotizing ulcerative gingivitis

53
Q

characteristics of Fusobacterium nucleatum

A

gram negative

anaerobic, spindle-shaped rod

54
Q

F. nucleatum is an ____ in plaque and is a ____ organism

A

early colonizer; bridging

55
Q

F. nucleatum can induce cell death in ____; releases ____, ____, and ____ from _____

A

leukocytes

releases cytokines, elastase, and oxygen radical from leukocytes

56
Q

Gram-negative, capnophilic, assacharolytic, regular, small rod with blunt ends

A

Eikenella corrodens

57
Q

Gram-negative, anaerobic, short, motile vibrio

A

campylobacter rectus

58
Q

Gram-positive, anaerobic, small, assacharolytic coccus

A

peptostreptococcus micros

59
Q

Gram-negative, curved, saccharolytic rods

A

selenomonas species

60
Q

Gram positive, anaerobic, small, pleomorphic rods

A

Eubacterium species

random (33 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions