aggressive periodontitis Flashcards
localized aggressive periodontitis most frequently occurs between ____ and _____
puberty; 20 years of age
LAP characterized by localized CAL in ____ and _____
first molars; incisors (at least one first molar must be affected
in LAP, no more than ____ other than first molars and incisors are affected
2 teeth
there is a robust _____ response in LAP and the disease is _____
serum antibody (IgG2) ; self-limiting
generalized aggressive periodontitis affects individuals under the age of _____, but older patients may also be affected
30
distribution of GAP
at least 3 permanent teeth other than first molars and incisors
there is a pronounced ____ nature of the destruction of attachment/bone in GAP
episodic
in GAP, there is relatively intense _____ and poor ____
gingival inflammation (less intense in LAP); serum antibody response
prevalence of AP in the primary dentition is reported between ____ and ____
0.9% ; 4.5%
prevalence of AP in the permanent dentition is estimated at ____ (in the us and other countries)
below 1%
the prevalence for AP in both primary and permanent dentitions is higher among _____
african americans (about 2.6%)
____ is associated with LAP, particularly the ____
A.a. ; JP2 clone, serotype b
characteristics of A.a.
gram negative, facultative anaeroble, non-motile rod
virulence factors of A.a.
leukotoxins (kill PMNs and macrophages)
LPS: activates cells to produce PGs, IL-1b, TNFa
collagenases- degrades collagen fibers
immunosuppressive factors (lymphocyte/chemotactic suppressing factors)
A.a. translocates across the ____ and invades the _____
JE; CT
