pediatric immunity Flashcards
A nurse practitioner is educating a group of students on phagocytic disorders. Establish why further education is needed.
The most common sites of infection are the respiratory tract and skin.
Phagocytic disorders result from abnormalities in monocytes or neutrophils.
Infants may experience poor wound healing.
The musculoskeletal system is most frequently impacted.
The musculoskeletal system is most frequently impacted.
When educating a parent on primary immune disorders (PIDs), what statement is accurate?
Maternal autoimmune neutropenia can result in neonatal neutropenia resulting in PID.
Neonatal hypogammaglobulinemia caused by immunoglobulin loss into the gastrointestinal tract is an indication of PID.
Primary immune disorders are categorized by the compartment(s) of the immune system that is affected.
In utero exposure to immunosuppressive medications given to the mother can result in PID.
Primary immune disorders are categorized by the compartment(s) of the immune system that is affected.
A nurse practitioner is evaluating a patient for complement disorders. Propose an indication for patient screening.
Failure to thrive and thrombocytopenia
Recurrent unexplained infections of the respiratory tract and skin
Infants presenting with severely impaired neutrophil function
Multiple family members with Neisseria infections
Multiple family members with Neisseria infections
A nurse practitioner is educating a group of students on secondary immunodeficiency in children. Determine an accurate statement regarding secondary immunodeficiency.
Secondary immunodeficiencies are far more common than primary immunodeficiencies.
Hypogammaglobulinemia contributes to the state of secondary immunodeficiency and susceptibility to infections.
High-dose corticosteroids can be used prophylactically to prevent secondary immune disorders.
Neonates have decreased susceptibility to secondary immune disorders.
Secondary immunodeficiencies are far more common than primary immunodeficiencies.
A nurse practitioner is concerned about a patient presenting with an antibody disorder. Establish an accurate statement regarding antibody disorders.
Antibody disorders are characterized by the absence or presence of B cells.
Severe combined immunodeficiency (SCID) is the most severe form of antibody disorders.
Antibody disorders involve infections with encapsulated organisms and are often characterized by Neisseria infections.
Antibody disorders manifest as an unusual sensitivity to viruses.
Antibody disorders are characterized by the absence or presence of B cells.
A nurse practitioner is evaluating a child presenting for failure to thrive. Determine the patient who should be evaluated for a primary immune deficiency.
A newborn recently delivered after the mother experienced placenta previa
A 3-month-old with a family history of primary immune disorders
A newborn exposed to cytomegalovirus in utero
A premature infant with anemia
A 3-month-old with a family history of primary immune disorders
A nurse practitioner is concerned about a patient presenting with an antibody disorder. Recommend the laboratory screening for a patient presenting with an antibody disorder.
IgE
Factor VIII
T cells
Neutropenia
IgE
A nurse practitioner is evaluating an infant for severe combined immunodeficiency (SCID). Propose an accurate statement.
Treatment is not indicated in infants presenting with SCID.
Chronic granulomatous disease is common in patients with SCID.
It is the most severe form of T cell disorders.
Treatment typically involves high-dose antibiotics and radiation therapy.
It is the most severe form of T cell disorders.
A nurse practitioner is concerned about a patient presenting with an antibody disorder. Establish an accurate statement regarding antibody disorders.
Antibody disorders usually present once maternal immunoglobulins from placental transfer are no longer present.
Infants with antibody immunodeficiency have deficiencies of both T cell and B cell immunity.
Severe combined immunodeficiency (SCID) is the most severe form of antibody disorders.
Antibody disorders involve infections with encapsulated organisms and are often characterized by Neisseria infections.
Antibody disorders usually present once maternal immunoglobulins from placental transfer are no longer present.
A nurse practitioner is reviewing T cell disorders in children. Propose an accurate statement regarding T cell disorders.
Congenital neutropenia is a common T cell disorder.
DiGeorge syndrome is a T cell disorder.
Celiac disease is commonly seen in infants with T cell disorders.
Most T cell deficiencies present early in life.
Most T cell deficiencies present early in life.
A nurse practitioner is educating a group of students on secondary immunodeficiency in children. Predict what is consistent with a patient presenting with secondary immune deficiency.
A 6-month-old with a family history of chronic granulomatous disease
A patient presenting with Type 2 diabetes
A newborn presenting with low or deficient levels of any of the immunoglobulins
A newborn with a history of recurrent life-threatening infections
A patient presenting with Type 2 diabetes
When providing education on primary immune deficiencies, the nurse practitioner notes that these can be identified as what?
Acquired disorders resulting from a compromised immune system
Diseases of the immune system itself
A weak immune system as a result of another condition
Most often diagnosed in children and adolescents
Diseases of the immune system itself
A nurse practitioner is evaluating a patient for complement disorders. Propose an indication for patient screening.
Female patients presenting without lymph nodes
Recurrent Neisseria infections at any age
Failure to thrive and thrombocytopenia
Infants presenting with severely impaired neutrophil function
Recurrent Neisseria infections at any age
A nurse practitioner is educating a group of students on secondary immunodeficiency in children. Determine an accurate statement regarding secondary immunodeficiency.
Hypogammaglobulinemia contributes to the state of secondary immunodeficiency and susceptibility to infections.
The immune defects observed in secondary immunodeficiency are usually heterogeneous in their clinical presentation.
High-dose corticosteroids can be used prophylactically to prevent secondary immune disorders.
Antibody disorders are the most common secondary immune disorders.
The immune defects observed in secondary immunodeficiency are usually heterogeneous in their clinical presentation.
Determine an accurate statement regarding disorders of the complement system.
A complete blood count with differential is the gold standard of care.
The complement system is unable to kill catalase-positive organisms, including Staphylococcus aureus.
Neutropenia suggests a complementary disorder.
A CH50 assay is used to test the classic pathway that involves C1–C9.
A CH50 assay is used to test the classic pathway that involves C1–C9.
