Pediatric Disorders of Platelets and other Clotting Disorders

Question 1

Propose what is required to diagnose a child with ITP.

Magnetic resonance imaging

CT scan of the brain

X-rays of all major joints

Screening for autoimmune disorders

Answer 1

Screening for autoimmune disorders

Question 2

Explain why a clinician would consider administering IVIg in a child with ITP.

It can temporarily stop the spleen from destroying platelets.

It results in preferential destruction of red blood cells.

It is for dangerously low platelet counts.

It increases platelet counts in 3 weeks.

Answer 2

It is for dangerously low platelet counts.

Question 3

Determine a complication of hemophilia.

Diabetes

Blindness

Cataracts

Hemarthrosis

Answer 3

Hemarthrosis

Question 4

Identify a secondary cause of thrombocytopenia.

Erythroblastosis

HIB

Leukemia

Non-Hodgkin’s lymphoma

Answer 4

Leukemia

Question 5

Identify a symptom in a child with a platelet count of 20,000 per μl.

Intracranial hemorrhage

Petechiae on the arms

Lower gastrointestinal bleeding

Spontaneous hematoma in the mouth

Answer 5

Petechiae on the arms

Question 6

Determine a risk factor that may predispose a child toward chronic ITP.

Acute URI prior to onset of ITP

Episode of acute ITP

Younger age at onset

Immunocompromised status

Answer 6

Immunocompromised status

Question 7

Predict a side effect of Nplate.

Increased appetite

Fever

Chills

Joint pain

Answer 7

Joint pain

Question 8

Propose a common side effect of Rh immune globulin.

Somnolence

Muscle weakness

Nausea

Abdominal bloating

Answer 8

Nausea

Question 9

Determine a complication of hemophilia.

Cataracts

Dizziness

Deep internal bleeding

Diabetes

Answer 9

Deep internal bleeding

Question 10

Recommend an activity that a child with hemophilia should avoid.

Bowling

Tennis

Wrestling

Swimming

Answer 10

Wrestling

Question 11

Choose an appropriate treatment for a child with ITP.

Administering heparin subcutaneously

Offering aquamephyton three times per week

Giving a prothrombin complex

Administering a corticosteroid

Answer 11

Administering a corticosteroid

Question 12

Identify a type of hemophilia.

Hemophilia A

Acquired hemophilia B

Acquired hemophilia C

Autoimmune hemophilia

Answer 12

Hemophilia A

Question 13

Identify a characteristic of ITP in a child.

It is an autoimmune disorder.

All childhood cases progress to chronic ITP.

There is no risk of death associated with ITP.

ITP always presents with leukopenia.

Answer 13

It is an autoimmune disorder.

Question 14

Determine an infectious cause of ITP for which antibody testing and polymerase reactions may be helpful for diagnosis.

SARS

Cytomegalovirus

MERS

Zika virus

Answer 14

Cytomegalovirus

Question 15

Propose what is required to diagnose a child with ITP.

CT scan of the brain

X-rays of all major joints

Electrophoresis of all blood components

Complete physical examination

Answer 15

Complete physical examination

Question 16

Identify a characteristic of individuals with non-severe hemophilia.

They carry a lifelong risk for serious complications.

There is spontaneous heavy bleeding.

They bleed as much as those with more severe forms of hemophilia.

There are abnormal bleeding times.

Answer 16

They carry a lifelong risk for serious complications.

Question 17

Explain why a clinician would consider administering IVIg in a child with ITP.

It can temporarily stop the spleen from destroying platelets.

It prevents bleeding by decreasing platelet destruction.

It works more quickly than steroids.

It results in preferential destruction of red blood cells.

Answer 17

It works more quickly than steroids.

Question 18

Identify a secondary cause of thrombocytopenia.

Erythroblastosis

HIV

Aplastic anemia

Non-Hodgkin’s lymphoma

Answer 18

HIV