PCOS Flashcards
1
Q
What is PCOS?
A
Polycystic ovary syndrome
Endocrine disorder
2
Q
What are the endocrine abnormalities in PCOS?
A
Excess LH -> increased production of androgens
Insulin resistance
3
Q
What are the features of PCOS?
A
Oligo/amenorrhoea Infertility Obesity Hirsutism Acne
4
Q
How is diagnosis of PCOS made?
A
Rotterdam criteria
5
Q
What are the Rotterdam criteria?
A
Need 2 out of 3
- oligo/anovulation
- hyperandrogenism
- polycystic ovaries on USS
6
Q
What investigations are done for suspected PCOS?
A
Bloods
- raised testosterone
- low sex hormone binding globulin
- LH + FSH
- progesterone
- TFTs
OGTT
Transvaginal USS
7
Q
What is seen on TV USS in PCOS?
A
12 or more cysts
Ovarian volume >10cm3
8
Q
How is PCOS managed generally?
A
Weight loss
Lifestyle advice
Patient education
9
Q
How is oligo/amenorrhea managed in PCOS?
A
COCP
Cyclical progesterone
10
Q
How is infertility managed in PCOS?
A
Clomiphene
Metformin
11
Q
How is hirsutism/acne managed in PCOS?
A
COCP
Topical eflornithine
12
Q
What are the complications of PCOS?
A
Insulin resistance Acanthosis nigricans CVS disease Depression Infertility
