Ovarian Cancer Flashcards

1
Q

What are the types of ovarian cancer?

A

Epithelial cell

  • serous
  • mucinous

Germ cell

  • teratoma
  • dysgerminoma
  • yolk sac

Sex cord / stromal

Metastasis
- Krukenberg tumour

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2
Q

What is secreted by a dysgerminoma?

A

HCG

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3
Q

What is secreted by a yolk sac tumour?

A

AFP

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4
Q

What are risk factors for ovarian cancer?

A
Unopposed oestrogen 
Increasing age
Obesity 
BRCA 1/2
Smoking 
Clomiphene
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5
Q

What are protective factors against ovarian cancer?

A

COCP
Pregnancy
Breastfeeding

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6
Q

What are features of ovarian cancer?

A

Often non-specific

Bloating
Pain
N+V

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7
Q

What are 2ww referral criteria for ovarian cancer?

A

Ascites
Pelvic mass
Abdo mass

Raised ca-125

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8
Q

How is suspected ovarian cancer investigated?

A

Ca-125

Pelvic USS

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9
Q

What are indications for measuring ca-125?

A
Change in bowel habit
Abdominal bloating
Early satiety
Pelvic pain 
Weight loss
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10
Q

How is ovarian cancer managed?

A

Surgery

Chemo

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