Ovarian Cancer Flashcards
1
Q
What are the types of ovarian cancer?
A
Epithelial cell
- serous
- mucinous
Germ cell
- teratoma
- dysgerminoma
- yolk sac
Sex cord / stromal
Metastasis
- Krukenberg tumour
2
Q
What is secreted by a dysgerminoma?
A
HCG
3
Q
What is secreted by a yolk sac tumour?
A
AFP
4
Q
What are risk factors for ovarian cancer?
A
Unopposed oestrogen Increasing age Obesity BRCA 1/2 Smoking Clomiphene
5
Q
What are protective factors against ovarian cancer?
A
COCP
Pregnancy
Breastfeeding
6
Q
What are features of ovarian cancer?
A
Often non-specific
Bloating
Pain
N+V
7
Q
What are 2ww referral criteria for ovarian cancer?
A
Ascites
Pelvic mass
Abdo mass
Raised ca-125
8
Q
How is suspected ovarian cancer investigated?
A
Ca-125
Pelvic USS
9
Q
What are indications for measuring ca-125?
A
Change in bowel habit Abdominal bloating Early satiety Pelvic pain Weight loss
10
Q
How is ovarian cancer managed?
A
Surgery
Chemo